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Current Trends in Male Performance Enhancement: What Works

Sexual performance with Elite Sarms

In our previous blog, we explored the best natural supplements to improve male performance in the bedroom, and the science behind their response in the body. In this article, we put the spotlight on the latest pharmaceutical products in the market of enhancing sexual performance and stamina in males.

https://www.elitesarms.com/blogs/news/best-supplements-for-improving-bedroom-performance-science-based

PDE5 Inhibitors

Majority of the pharmaceutical compounds used to treat erectile dysfunction and enhance libido work by stimulating blood flow to the penis – similarly to how we use nitric oxide increasers in pre-workout to enhance our muscle pumps in the gym. Oral formulations of Phosphodiesterase type 5 (PDE5) inhibitors are the most common in this category and work to block the breakdown of cyclic guanosine monophosphate (cGMP). This prolongs the signalling of vasodilation molecules including; nitric oxide (NO) resulting in longer erections.

It is important to note that individuals who are taking nitrate drugs for chest pain or using alpha-blockers to treat high blood pressure should not take PDE5 inhibitors, as this can lead to a sudden decrease in blood pressure, which can become a danger.

https://www.elitesarms.com/collections/sexual-performance/products/elite-sarms-hard-stack-sildenafil-50mg-ml
https://pubmed.ncbi.nlm.nih.gov/31643519/ https://www.healthline.com/health/heart-disease/drugs https://www.healthline.com/health/high-blood-pressure-hypertension-medication

Sildenafil

Sildenafil (Viagra) is a popular PDE5 inhibitor, mainly due to its shorter activation time and shorter half-life. A 2002 study showed that it takes roughly 27 minutes for Sildenafil to kick in. That is relatively fast if one is looking to be spontaneous in sexual activity.

Depending on individual metabolism, Sildenafil can take 4 to 6 hours to fully leave your system. For the most part, Sildenafil can be taken for on-demand usage but if you’re looking for a daily dosage, 50mg a day is considered a safe dose.

https://www.elitesarms.com/collections/individual-sarms/products/elite-sarms-hard-sildenafil-50mg-ml
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874251/


Tadalafil

Tadalafil (Cialis) is another PDE5 inhibitor, but slightly different compared to Sildenafil. Tadalafil’s activation period takes 1-2 hours after taking it, meaning one will have to wait longer to get fired up. This is more suited to unplanned intimacies like a night out or weekend trips – in fact Tadalafil has been dubbed “The Weekender”.

Since Tadalafil takes longer to activate, this also means it has a longer half-life. Tadalafil has an active half-life for up to 17.5 hrs resulting in erectile responsiveness for up to 36 hours with a single dose! A 2016 study established its safety and efficacy whether taken as needed, or on a daily basis.

https://www.elitesarms.com/products/tadalafil?_pos=1&_sid=8145ab6b4&_ss=r https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411983/

Penile Suppositories

Alprostadil – Penile Suppository

Yes this a real thing! Alprostadil known as – MUSE – comes as a penile suppository, meaning it is placed in the urethra. MUSE, or (Medicated Urethral System for Erections), is available as a pill or injection. Alprostadil is in the vasodilator family of compounds. The pill version is inserted into the urethra, which is the opening at the tip of the penis and in 5-10 minutes, it activates by causing blood vessels to expand, by relaxing smooth muscle and allowing more blood flow into the shaft.

Despite Alprostadil’s maybe not-so-enjoyable application method, this is an important medication for males with Erectile dysfunction (ED) because it is usable by men suffering from diabetes or heart problems and those who have undergone a prostatectomy. It has no known interactions with food, alcohol or other medications making it safer than other treatments, such as the injection form, containing alprostadil.

https://pubmed.ncbi.nlm.nih.gov/9738294/
https://en.wikipedia.org/wiki/Prostaglandin_E1


Peptide Injections

PT-141 (Bremelanotide)

PT-141 is an FDA- approved injectable (stomach area) medication specifically effective for hypoactive sexual desire disorder (HSDD). This drug is different and exciting because it works directly on the hypothalamus in the brain to increase sexual desire. This makes it effective on men and just as effective on women, having a persistent or recurrent deficiency or absence of sexual fantasies, thoughts, and desire.

Think of it as an aphrodisiac that targets neural pathways of the brain to increase your libido…

For best effects, patients should inject PT-141 around 45 minutes before sexual activity. While this peptide carries huge potential in the treatment of erectile dysfunction and hypoactive sexual desire disorder (HSDD), it should not be used more than once in a 24 hour period or more than 8 times in a month – according to health professionals.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819023/ https://www.fda.gov/news-events/press-announcements/fda-approves-new-treatment-hypoactive-sexual-desire-disorder-premenopausal-women

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Best Supplements for Improving Bedroom Performance (Science-based)

ES EDM BLOG

Performance in the bedroom is import for males. Sexual prowess is strongly related to a man’s self-esteem, which further explains why the typical male feels powerful when he performs well and deflated when performance is not up to the preferred level.

If you have a low libido or fertility issues, you’re not alone. Clinical studies suggest that sexual dysfunction is common – 43% of women and 31% of men encounter some degree of dysfunction throughout their lifetime. It is a delicate topic that some people are embarrassed to talk about and yet its prevalence has generated a lot of public interest. Thus, there is a substantial demand for remedies, compounds and medications to address sexual dysfunction.

https://pubmed.ncbi.nlm.nih.gov/11122954/

Supplements for Enhancing Male Performance

Supplement 1: Maca Powder

The maca plant, scientifically known as; Lepidium meyenii, is popularly referred to as the Peruvian ginseng. The plant’s root was traditionally employed to enhance fertility and sex drive, thanks to its tonic properties. The Peruvian plant, which also belongs to the Brassica family, also claims to improve energy and stamina.

It grows exclusively between 4000 and 4500m in the central Andes, weathering harsh conditions and at very high altitudes.

Compared to placebo, Research shows that Maca effectively enhances sexual drive in both male and female subjects. According to lab studies, Maca can also invigorate spermatogenesis by affecting the initial stages of sperm production. This improves sperm volume and quality, which then enhances fertility in men.

The Maca root powder is high in protein, carbs, vitamin C, copper, and iron, and is also popularly used as a mood enhancer.

https://pubmed.ncbi.nlm.nih.gov/20691074/

https://pubmed.ncbi.nlm.nih.gov/11561196/


Supplement 2: Panax Ginseng

This plant mainly grows in Asia, and is sometimes known as Asian ginseng, Chinese ginseng, or Korean red ginseng. Panax ginseng is typically utilised as an herbal tonic to increase alertness and improve libido.

Research studies support that Panax ginseng may be an effective alternative treatment for erectile dysfunction. The main mechanism behind its effectivity is enhanced levels of nitric oxide synthesis in the corpus cavernosum, the erectile tissue in the penis. The enhanced nitric oxide levels effect further vasodilation, thus causing the aphrodisiac action of the root.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561113/

Supplement 3: Yohimbine HCl

West African traditional medicine also has its own remedy for sexual tonic – Yohimbe is a herbal supplement which boasts a long history of use to improve sexual performance. The supplement is derived from the bark of an evergreen tree found in Western and Central Africa called the Pausinystalia johimbe.

Yohimbine, pharmacologically classified as an alpha-2-adrenoceptor antagonist, works by blocking adrenergic receptors – which play an important role in inhibiting erections. Hence, yohimbine may help alleviate erectile dysfunction. According to another clinical trial, Yohimbine’s response on participants resulted in; improved rigidity on the RigiScan test and slightly higher levels of serum testosterone – which makes Yohimbine a promising therapy to organically treat erectile dysfunction and low libido.

https://pubmed.ncbi.nlm.nih.gov/10845767/

https://pubmed.ncbi.nlm.nih.gov/11896474/

Supplement 4 and 5: Sildenafil and Tadalafil

One of the most common questions related to ED medicines like Sildenafil (Viagra) and Tadalafil (Cialis), is how they affect the sexual experience. Do they change the way sex feels or have any impact on sexual enjoyment or performance?

The mechanism behind Sildenafil (Viagra) is fairly simple. It is a PDE5 inhibitor, meaning it inhibits the particular enzyme that controls blood flow to the soft tissue of the penis. When you take Sildenafil, the blood vessels that supply blood to and around the penile shaft dilate, allowing more blood flow and making it easier to get an erection.

Sildenafil won’t make you spontaneously get an erection unless you’re sexually aroused, physically or mentally. Instead, it just makes it easier for your body to develop and maintain an erection by improving blood flow to the tissue of the penis.

A 2007 study noted that Sildenafil is “effective and safe” for treating premature ejaculation, which means it has a positive effect on the amount of time you can last. Sildenafil facilitates developing and sustaining an erection, which means once aroused, even when you’re feeling anxious or poorly stimulated, you’re less likely to lose your erection during sex.

Sildenafil usually leaves your system after 2 to 3 hours. Depending on your metabolism, it can take 5 to 6 hours to fully leave your system, which makes it the perfect supplement if you’re looking for Supreme male performance in the bedroom.

You can find Sildenafil in the Elite Sarms range Here:

https://www.ncbi.nlm.nih.gov/pubmed/17470165

https://www.healthline.com/health/erectile-dysfunction/how-long-does-viagra-last

RISE to the Occasion

Cyclic guanosine monophosphate (cGMP) is a nucleotide responsible for relaxing smooth muscle tissues. In our blood vessels, when the vascular smooth muscles relax, this leads to vasodilation and increased blood flow.


Tadalafil
(Cialis) works by preventing the breakdown of cGMP, which significantly means more vasodilation and subsequently greater blood flow to the sexual organs. What’s cutting edge about Tadalafil over other PDE5 inhibitors is its high selectivity. As a matter of fact, Tadalafil has 700x more selectivity compared to Viagra (7x) and Levitra (3x). This means Tadalafil doesn’t have some of the negative side effects that can come about such as; headache, pressure behind the eyes, stuffy nose or vision problems which can occur from other PDE5 inhibitor compounds.


Amazing fact about Tadalafil:
It has an active half-life for up to 17.5 hrs resulting in erectile responsiveness for up to 36 hours with a single dose! Compared to other male enhancement products which work for about 4-6 hours, one dose of Tadalafil will ensure that by all means, your stamina in the bedroom will be truly epic!

You can find Tadalafil in the Elite Sarms range Here:



https://www.elitesarms.com/collections/sexual-performance/products/tadalafil

https://www.drugs.com/monograph/tadalafil.html

https://pubchem.ncbi.nlm.nih.gov/compound/Tadalafil#section=Top

https://pubmed.ncbi.nlm.nih.gov/19756466/#:~:text=In%20contrast%20to%20other%20currently%20available%20PDE5%20inhibitors,up%20to%2036%20h%20after%201%20single%20dose.