Tag: Future Supplements

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Anti-Aging Biohacks for Athletes of Any Age

ES EDM BLOG 0998f27a 1601 40de 8535 14306a96657f

By: M.G. Thibault. Edited by Ryan McTeigue

Whether you are in your 20’s or whether you are in your 50’s it doesn’t matter. The following hacks below won’t just make you feel younger, they will help your body regenerate, recover and for the ladies there is even some beauty biohacking thrown in here. These trends in Age-reversal and body amplificationcome and go especially with new scientific discoveries and advancements in medicine.

However, the best way to find out which modality is right for you is through careful research and professional consultation so you can discuss your goals and customize a hormone and cellular enhancing program tailored to your lifestyle, genetics, needs, and budget.

Here are the most promising non-invasive anti-aging treatments and devices predicted to go big according to our Intel’s forecast.

Infrared Sauna

Infrared Sauna. Scientists at Stanford-Burnham Prebys Institute confirms that sauna use have beneficial effects on health and longevity. What happens is when you expose the body to high temperatures of about 120°-180° F, it creates heat shock proteins and stimulates the lymph system, which detoxifies the system and increases microcirculation. Far Infrared saunas (FIR) are waves of energy, entirely invisible to the naked eye, which infiltrate the surface of the skin where they slightly elevate the body’s surface temperature. FIR are shown to reduce inflammation and oxidative damage, and has the potential to alleviate health conditions that arise with aging.

https://www.sciencedaily.com/releases/2017/02/170215084050.htm

https://www.hightechhealth.com/longevity-benefits/

Stem Cell Facelift. This revolutionary treatment provides the regenerative benefits of stem cell therapy for anti-aging purposes, but entails no surgery and no downtime. A new study finds that after just a few weeks, stem cell treatment eliminates the skin’s sun-damaged elastin network, and replaced with normal, undamaged tissues.

Basically, stem cells migrate to sites of inflammation to dramatically calm down the inflammatory cascade and then lay down a new cellular framework. This treatment yields dramatic skin renewal and a natural lift that can last 3 years.

https://www.sciencedaily.com/releases/2020/05/200528160510.htm

https://journals.lww.com/plasreconsurg/Abstract/2020/06000/Photoaged_Skin_Therapy_with_Adipose_Derived_Stem.12.aspx

Endermologie

Endermologie. Endermologie is a noninvasive mechanical body-contouring used in the treatment of cellulites. Here the cellulite-affected skin is sucked between the rollers and kneaded for approximately 34-45 min. Endermologie was initially developed in the late 1970s in France to soften scars and standardize physical therapy; however, other benefits were seen in patients treated with the LPG machinesuch as improvement in body contour and skin texture, reducing the appearance of cellulite and retaining the youthful suppleness of the body.

https://www.tandfonline.com/doi/abs/10.1080/14764170510037761

https://pubmed.ncbi.nlm.nih.gov/9502849/

Bioidentical Hormone Replacement Therapy

Bioidentical Hormone Replacement Therapy. Bioidentical hormone replacement therapy (BHRT) is a popular modality when it comes to effectively treating hot flashes, mood swings, low libido, and a decline in energy- all of which are symptoms that accompany aging.

Our production of certain hormones begins to decrease as early as our mid 30’s. As one gets older, this decrease in certain hormones changes the way cells and tissues function leading to a myriad of uncomfortable symptoms. BHRT is also a reliable treatment for osteoporosis, thinning hair, poor memory, and other forms of chronic inflammation, that may be observed in both men and women.

BHRT helps correct hormonal deficiencies by providing the body with hormones that have the exact same chemical and molecular structure as those endogenously produced by the body. BHRT is a perfect example of how rejuvenation treatments can help clients age more gracefully and painlessly. BHRT has gotten a lot of attention in recent years as they promise a “natural” solution to hormone issues. One example is Biotropin® HGH synthesized via recombinant technology, which has the exact protein structure of your natural growth hormone, and is made up of 191-amino acids.

A Biotropin® HGH replenishment course boosts Somatropin levels and effectively stimulates tissue repair, cell renewal, and sustain brain and other organ functions thus alleviating the typical symptoms that come with ageing.

https://www.healthline.com/health/bioidentical-hormone-replacement-therapy

https://www.onlinebiologynotes.com/production-human-growth-hormone-hgh-recombinant-dna-technology/

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Circadian Rhythm and Rejuvenation. How Re-Setting The Rhythm Can Potentiate Your Entire Body

ES EDM BLOG 1964e506 c777 4bb0 bcb6 26fcafcb8ba7

By: M.G. Thibault. Edited Ryan McTeigue

Your Circadian rhythm controls many aspects of your health from sleep to heart rate, hormone secretion, blood pressure, neurological function, and metabolic routes. As you can see many things which can either improve of decrease an athletes performance.

Today, researchers are learning that the circadian rhythm can also be a new target to help rejuvenate the whole body and extend lifespan. This area of research holds so much potential that lab studies from MIT discovered a link between a healthy circadian rhythm and the constant rejuvenation of an organism. Scientists are positive that by enhancing the body’s circadian cycle, one can prevent and treat diseases not only due to aging but disorders that arise from very active (fitness lovers) or strenuous lifestyles (most humans on earth).

You can’t really exaggerate the importance of this research since many health conditions arise from the disruption of our circadian rhythms especially in these modern times. These increasing disturbances in one’s “body clock” is strongly linked with inflammatory states including neurodegenerative diseases.

Whether disorders in the body arise from stressful daily routines, environmental toxins, excessive physical demand, or simply from aging, at the molecular level, thanks to our scientific community, a person can now restore the body’s circadian rhythm to a more youthful state and effect complete rejuvenation in the body.

https://news.mit.edu/2013/the-link-between-circadian-rhythms-and-aging-0620

https://pubmed.ncbi.nlm.nih.gov/27885006/

Based on the ongoing stream of confirmatory data, there are particular compounds that can help synchronize and restore the proper operation of the body’s circadian rhythm. This article will prove to be of great value if you feel out-of-sync with your current sleeping habits. This article is for the following person who is:

– Consistently working out

– Regularly engaging in sports or outdoor activities

– Involved in mentally demanding tasks as part of the job

– Constantly multi-tasks in a daily basis

– Looking to increase their productivity levels

– Gearing up for a more challenging workload ahead

– Experiencing problems due to inflammatory conditions

– Already feeling age-related effects in performance

If one of more factors on this list describe YOU, your priority right now is to regain control over the proper function of your circadian rhythm in order to re-claim your essential health and rejuvenate your body to its highest level. Below we outline a few hacks which can greatly help with this task::


1. Melatonin

Scientists have found that we can keep our circadian clock in sync through melatonin supplementation. This unique nutritional approach targets both central and peripheral clocks to regulate circadian rhythm. When the brain’s pineal gland secretes melatonin, this helps normalize hormone production, neurotransmitter functions and healthy sleep patterns.

A 2017 study shows that daily supplementation of 10 mg of Melatonin in subjects with obesity decreased oxidative stress and facilitated body weight reduction while improving the body’s antioxidant defence. This factor translates to healthy, normal individuals as well.

https://pubmed.ncbi.nlm.nih.gov/25287733/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632922/

2. SIRT 1 activators

Researchers have shown that SIRT1 (Sirtuin) helps regulate circadian rhythm and protect against the diseases of aging. The SIRT1 gene is also shown to protect against diseases of aging and plays a key role in controlling the body’s circadian rhythms. Conversely, loss of SIRT1 function impairs circadian control in young mice, mimicking what happens in normal aging. Activating the SIRT1 pathway to sustain adequate circadian control and thus reverse aging is a probable therapeutic target that Regenerative Medicine is currently looking into.

By activating the SIRT1 pathway, damage in our DNA created by environmental factors, stress, energy deprivation, and toxins that the body accumulates are constantly being replenished and cell division continues to ensue.

Sirtuin-activating compounds include ginseng, resveratrol, quercetin, polyphenols found in bitter vegetables, cacao, curcumin, ginger, and DHA sourced from fatty fish, eggs, and algae. So ensure you add greens to your daily meals and consider into adding the aforementioned herbal and food supplements into your weekly routine – test it out and see if you feel better after at least 14 days of consistent usage.

https://pubmed.ncbi.nlm.nih.gov/32084459/

3.Rev-erb-α Agonists

Rev-erb-α is critical for the proper timing of the core clock machinery, regulating many metabolic functions, which include lipid and bile acid metabolism, gluconeogenesis, and the body’s inflammatory response. Rev-erb-α ligands, specifically agonists or activators, modify the transcriptional activity (telling the body what to do) and suggest that Rev-erb-α may serve as a promising target for the treatment of circadian alterations of metabolic pathways.

Rev-erb-α modulation was proven to be efficient in phase-advance sleep disorders commonly seen in the aging population, while it helps correct delayed circadian rhythms, frequently seen in individuals with super-active or very stressful lifestyles. In short compounds such as SR9009 can help to balance the circadian rhythms in both sleep deprived and overly-active individuals – assisting in rejuvenation and regeneration of the entire body. Leading to more energy to train, work and do more of the things you love doing!

Rev-Erbα agonists such as Hyper Lean SR9009 has been proposed to coordinate circadian metabolic responses while maintaining the timely schedule of wakefulness, sleep, body temperature, and hormone regulation which in turn facilitates a myriad of biochemical pathways. Therefore, Rev-erb-α ligands may be useful in resetting the Circadian clock into its youthful resonance and efficiency.

You can find Elite Sarms Rev-erb-α Agonist Hyper Lean® (SR9009) here.

Sweet dreams,

-ES


https://www.elitesarms.com/collections/individual-sarms/products/hyper-lean-sr9009

https://journals.physiology.org/doi/full/10.1152/japplphysiol.00570.2009

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Diverse Rejuvenation in a Bottle – Decavar MK-2866

ES EDM BLOG a17a6929 1270 4e37 8649 3cafae2fee24

By: M.G. Thibault. Edited: Ryan McTeigue

While scientists continue and progress in SARMs research, studies are increasingly assessing how to push the boundaries of SARMs development to maximize their potency, bioavailability, half-life and tissue selectivity, while minimizing side effects. Over 50 years of androgen research has resulted to one of the most cutting-edge SARM – MK-2866 (Decavar®).

MK-2866, otherwise known as Ostarine or Decavar® is a compound developed by the company Gtx Inc. In 2009, initially designed to fight muscle wasting diseases like cancers in all forms. MK-2866 went through numerous phases of trials from roughly 2005 through 2014. MK-2866 was studied and tested for its effectiveness against different medical conditions. It has a molar mass of 389.33g/mol and its melting point is 270°F to 277°F or 132°C to 136°C, rendering its stability even at higher temperatures, scientifically MK2866 is a sturdy compound.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907129/

https://www.elitesarms.com/collections/individual-sarms/products/decavar-mk2866

Pharmacodynamics of MK-2866

MK-2866 is an orally available non-steroidal SARM (all Sarms are non-steroidal despite having steroid like results, an amazing fact in and of itself) that has shown promising results in both preclinical and clinical trials, and is currently being studied for a number of different indications.

MK-2866, popularly known as Decavar is a selective androgen receptor modulator, which aims to increase the growth of muscle mass and improve strength. This main action occurring through the drastic increase of repair and rejuvenation of collagen. Collagen being the material located throughout the body in: muscle, bone, tendons, ligaments, organs, blood vessels, skin, intestinal lining and all other connective tissue. It’s this collagen increase and modulation of repair that attributes to Ostarines muscle building, muscle and joint rejuvenation, muscle conditioning and strength increasing properties. The compound also prevents muscle wasting that occurs in diseased states, fasted states and accompanies aging.


What is MK-2866’s mechanism of action?

MK 2866 is highly selective and only binds to bone and muscle androgen receptors while simultaneously modulating collagen as previously mentioned. What is so impressive about this novel substance is that it has multi-functional properties and the product can be used for not only building muscle mass, but for the regeneration of joints, muscles, and connective tissues. The substance proves to be a great bone regenerating supplement fortifying bones and prominently enhancing the strength and density of them. Structural improvements in post-menopausal female subjects were proven in lab testing resulting in bone improvements such as increased bone mineral density and increased bone volume density. You can then imagine the bone fortifying results a trained athlete will receive when the application of MK2866 is introduced to their training regime.

A 2019 study in the University of Life Science researched the effect of MK-2866 on fat cells of lab rats. The research results demonstrated:

The stimulation of androgen receptor expression. Whereby the metabolism was improved by facilitating the mRNA and protein expression of Androgen Receptors.

Decavar MK-2866 stimulates lipolysis. Investigations found that as little as 1 μM (micromole) of MK-2866, roused lipolysis in isolated rat adipocytes (fat cells) after just 120 and 480 minutes of incubation.

MK-2866 inhibits lipogenesis (fat creation). In animal studies MK-2866 displayed a marked effect on the halting of glucose (carbohydrates) to lipids (fats) in the lab. When MK-2866 is added to animal adipocytes (fat cells), it also inhibited (ceased or reduced) the rate of fat creation in those test subjects.

Decavar MK-2866 modulates the expression and secretion of leptin. Leptin is a hormone that sits in the stomach lining and basically tells the brain when you are full. When this signal is disrupted one will continue to eat beyond the bodies energy requirements – and disrupted leptin levels are the culprit of these signals to the brain telling one to eat more.

Leptin levels being low or disrupted (usually via consuming inflammatory creating foods) are directly associated with adipose tissue mass (fat tissue mass). Leptin concentrations are directly connected to cases such as obesity and cardiovascular diseases such as hypertension and myocardial infarction, both of which are more commonly seen in the aging population. Experiments showed that by administering MK-2866 to isolated rat adipocytes, leptin gene expression was normalised.

https://pubmed.ncbi.nlm.nih.gov/29785666/

http://www.jpp.krakow.pl/journal/archive/08_19/pdf/10.26402/jpp.2019.4.04.pdf

https://www.elitesarms.com/collections/individual-sarms/products/decavar-mk2866


Dosing

Most MK-2866 cycles last between 8 and 12 weeks. The cycle for beginners on average begins with a lower dosage of 10mg. With more experience in the use of SARMs, the dose can be increased, but the entire cycle should not last more than 12 weeks.

Decavar® is highly anabolic especially when paired with a well-calculated balanced diet including adequate, quality protein, good fats and complex carbs. Leaving the weekends or set days to eat outside these healthy foods and replenish the inner child through “cheat meal”. Then jumping straight back onto the horse and riding the nutrient rich diet once again. For us normal to serious training folk a good nutrition split is 80/20; 80% clean nutrition with 20% for not so clean, not so nutrient dense cheat meals. But that’s a whole other blog…….


Future Trends

The research community is now looking on esterification of MK-2866, a process in which the compound is altered to increase the half-life and biological action of the compound. So Instead of taking 1 dosage of Decavar® daily this could lead to only having to take 3, 2 or 1 dosages in a weekly period. Although this process is in the early experimental stages, the pharmacological optimization of one of the most documented and widely used SARMs – Decavar® (MK2866) offers a fresh take and may open up more exciting avenues for SARMs research.

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Elite Sarms Rejuvenation Biohacking Tech

ES EDM BLOG 80275cb0 1c01 4680 b69a 7768398acab8

By: M.G. Thibault Edited by Ryan McTeigue

Aging leads to a series of changes in an organism as deep as the cellular level. Although, the mechanisms that underlie aging are poorly understood, innovations in science continue to identify factors that explain the decline in fitness and the rise of different health problems that go with advancing age.

While slowing the aging process remains to be a popular topic, what’s even more compelling is the subject of Age-reversal; this is referred to as Rejuvenation.

Rejuvenation is a process that not only defers aging, but literally reverts it- resulting in a younger cell, tissue, or body. Rejuvenation includes diminishing all the damages your body has accumulated throughout its lifespan, and erasing the hallmarks of a matured age. Come to think of it, successful rejuvenation not only leads to the extension of life but ultimately to eternal youth! Does it look like something you’d be interested in? Read on…

https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.13483

Cell-regenerating Nutrition

Our body is an extraordinary machine and its primary fuel are the nutrients we get from the food we eat on a daily basis. By purposefully consuming foods that have ‘supercharging compounds’, a person can promote the rapid regeneration and restoration of some of the body’s most important tissues and organs.

Nerve-regenerative substances:
A 2010 study published in the journal Rejuvenation Research, for instance, found a combination of blueberry, green tea and carnosine have neuritogenic (i.e. promoting neuronal regeneration) and stem-cell regenerative effects in an animal model of neurodegenerative disease. Other researched neuritogenic substances include: curcumin, Lion’s Mane Mushroom, and apigenin, a plant flavonoid usually found in celery.

On the other hand, you can stimulate liver mass regeneration and function by ingesting via supplements that focus on liver renewal such as Korean Ginseng, Rooibos, Vitamin E, and Carvacrol, a compound found in oregano.

https://pubmed.ncbi.nlm.nih.gov/20586644/

http://www.thehealersjournal.com/2014/09/25/how-to-regenerate-your-bodys-cells-with-food-and-herbs/

https://pubmed.ncbi.nlm.nih.gov/24266378/

https://pubmed.ncbi.nlm.nih.gov/30949912/

Age-defying Exercises

According to a medical article, exercise improves muscle health by renewing the powerhouse of the cells: the mitochondria. Mitochondria are vital to the proper functioning of our bodies, and the improvement of our overall health and longevity.

Aerobic exercise, in particular, positively affects the mitochondria through a process called “mitophagy.” Mitophagy is a mechanism by which damaged or defective mitochondria are selected and removed, usually after a period of stress. This keeps skeletal muscle healthy and strong by improving the mitochondrial quality of the muscle fibers.

If you are a gym person- the treadmill, elliptical or rowing machine may be your go to equipment to achieve your fill of cardio exercises. Likewise, if you prefer the outdoors, you may try swimming, soccer, triathlons and cross country skiing as enjoyable alternatives to improve your aerobic capacity.

https://www.medicalnewstoday.com/articles/319532#Exercise-promotes-mitophagy-in-mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630798/

Supplements for Age-Reversal

In the ever-evolving world of Cellular rejuvenation, supplements are constantly being discovered and re-formulated. So far, the following are considered to be on top of the food chain when it comes to reverting the aging process:

There are secretagogues, which stimulates the endocrine glands’ ability to secrete more Growth Hormone, which in turn affects the major metabolic pathways in the body, such as fat oxidation, glucose utilization, muscle synthesis, and collagen production just to name a few.

Rejuvenation procedures in private clinics almost always integrate bio-identical Somatropin injections as part of their hormone optimization courses, while others employ drips and infusions of high doses of Vitamin C to regenerate hormones that have degraded. A powerful electron donor, vitamin C has the capacity to provide electrons in order to resurrect the form and function of estradiol, progesterone, and testosterone.

https://www.elitesarms.com/collections/anti-aging/products/gh-pep-mk677

https://www.healthline.com/health/vitamin-c-injection

Current Modalities on Rejuvenation

Ablative laser resurfacing is generally considered to be the gold standard for the rejuvenation of facial photo-damage and scarring. The procedure is a wounding laser that gets rid of the thin outer layer of skin (epidermis) and heats the underlying skin (dermis), which then triggers the growth of new collagen fibers. As the epidermis heals and regrows, the treated area appears smoother and tighter.

Neck rejuvenation mainly targets skin laxity, that often increase with age due to progressive loss of bone mass, increased subcutaneous fat, and loosening of the connective tissue framework. Using unipolar and bipolar radiofrequency or Infra-red light, sagging skin in the neck area is targeted yielding a tighter, firmer, and younger looking skin just after a few sessions.

A new paradigm for human cell rejuvenation, cellular reprogramming proves to be a promising route when it comes to retracting the procession of aging, which is the basis of rejuvenation.

This is the most recent breakthrough in the anti-aging field, which involves a genetic or chemical method to reverse the epigenetic age of cells. This genetic code instructs mature, specialized cells to read the right genes at the right time, as though they were young again. The factors scientists are currently using to reprogram these mature cells are called Yamanaka factors, which can turn back an adult cell into a young, pluripotent stem cell. Literally!


https://www.mayoclinic.org/tests-procedures/laser-resurfacing/about/pac-20385114

https://www.researchgate.net/publication/225927112_Treatment_of_Neck_Laxity_with_Radiofrequency_and_Infrared_Light

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960911/

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BioHacking Your Way To Your Best Physique 
- An Elite Sarms Future Supps Adventure –

ES EDM BLOG 53f2fedf 0f0a 4363 b9a6 a6dca3d82d05

By: M.G. Thibault Edited by Ryan McTeigue

It is true that you can’t increase the time and effort required to create your greatest physique ever, however you can maximize your efforts and go above and beyond traditional training programs to achieve a lean, strong and greatly developed physique, in comparison to the average person. In this article, we will discuss advanced supplement protocols and advanced training techniques that work in synergy so you can improve your overall workout productivity and move toward your best body achievement.

The following are the latest biohacking techniques that will allow you to achieve fitness, fat loss, and clean gains in minimum time using new discoveries about human biology, physiology and access to modern technology.

Glucagon-Like Peptide 1

Glucagon-Like Peptide 1 (GLP-1) agonists. GLP1 agonists have been demonstrated to recruit muscle microvasculature, increase muscle delivery of insulin, and enhance the muscles use of glucose. What this means for the fitness individual is that it increases both Insulin production and sensitivity which results in stronger anabolic action of the compound and better use of glucose for muscle tissue growth. If you are looking to increase insulin sensitivity and carbohydrate utilization by muscle, a GLP-1 agonist is a peptide which has to be administered subcutaneously (under the skin). Its ability to slow down gastric emptying makes you actually want to eat less, which will be ideal for a cutting cycle or a weight and fat loss program.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113068/

Blood Flow Restriction Training

Blood Flow Restriction Training. Also known as occlusion training, is the action of simply applying an elastic band or rubber tubing around the muscle you want to target which acts like a tourniquet. Then proceed with your training. Theoretically, when you cut a small amount of blood flow to the tissue, more lactic acid accumulates faster because it doesn’t drain due to the restriction. This triggers your Growth Hormone secretion effecting more muscle building action.

A meta-analysis confirms that exercise and walking with vascular occlusion played a key role in improving strength muscle hypertrophy which is in the ball park equivalent to training high-intensity resistance training. This is compatible with those having joint pain, older fitness people and/or athletes who are recuperating from injury and just getting back into the gym.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349784/

Oxygen Restricted Training

Oxygen Restricted Training. Advance your training by biohacking your breathing. This is done by restricting your access to oxygen thereby compelling your inspiratory and expiratory muscles to work harder to take oxygen in and push carbon dioxide out.

This creates a stronger diaphragm, tougher respiratory muscles, and a higher tolerance for carbon dioxide. The “intermittent hypoxic training mask” gives you the benefits of both resisted breathing and hypoxic training—yep, like working out in an environment with reduced oxygen, like a location at high-altitude. It’s like running a marathon at Mt. Kilimanjaro. When you exercise wearing oxygen restricting mask, this can push you to a whopping 95% of lactate threshold workload. And this is a sure-fire way to improve your aerobic capacity and endurance performance once you return to normal oxygen-level environments.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243200/

YK-11 Alpha Helix. It is one of the most innovative and exciting Selective Androgen Receptor Modulators in the market right now. This unique compound stimulates Follistatin and Myogenin production- molecules that are significantly responsible for skeletal muscle development and repair.

It also inhibits Myostatin, which is a negative regulator of muscle growth and is significantly implicated in muscle-wasting disorders. What this means is that Myostatin mainly inhibits and limits muscle growth. Thanks to YK11 Alpha Helix, it blocks the action of Myostatin stopping its catabolic effects while up-regulating follistatin and myogenin activities to allow muscle tissues to grow beyond their limitations.

Like any other SARMs, YK-11 Alpha Helix can be as powerful as testosterone in terms of muscle tissue strengthening and volumisation, but without any heavy side effects as with testosterone.


https://www.elitesarms.com/collections/individual-sarms/products/alpha-helix-yk11

https://www.sciencedirect.com/science/article/pii/S0006291X21000668

Remember:

The above tools will help you achieve faster physique targets as you enhance your training protocol for superior benefits. Don’t ever think these tactics are just for professional bodybuilders and athletes, these methods are simple enough and can be adopted by anyone to working to achieve their best physique yet.

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Discover The Power of Physique 400 (LGD4033)

ES EDM BLOG b62f28e0 00a9 4e1d b483 bbf3269e5ca5

Ligandrol, also known as LGD-4033 or Physique 400® in the Elite Sarms range, has been a favorite staple in the muscle building scene due to its reliable and consistent anabolic effects. This is due to Ligandrol’s high affinity to the androgen receptors of the bones, muscles, and connective tissues causing enhanced bone strength and accelerated muscle protein synthesis. This then equals large gains in strength and muscle mass at a highly accelerated pace compared to result times without it.

According to clinical data and anecdotal experiences, the most mentionable effects of Physique 400® are:

  • Lean Muscle Mass Gains
  • Accelerated Bulking Targets
  • Significant Boost in Athletic Performance
  • Fast increases in strength
  • Increased Bone Density
  • Enhanced Recovery Time
  • Improved SpeedOf Fat Loss

When tested on 76 healthy men for 21 days, LGD was safe and well tolerated, with noticeable increase in lean body mass, and despite the demonstrable androgenic activity, the serum PSA (The PSA test is a blood test used primarily to screen for prostate cancer. The test measures the amount of prostate-specific antigen (PSA) in your blood) did not change, proof that it has no adverse effects on the prostate. This only supports LGD’s low risk profile and high effectivity in low to average doses.

https://www.elitesarms.com/collections/individual-sarms/products/physique-400-lgd4033

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111291/

https://www.mayoclinic.org/tests-procedures/psa-test/about/pac-20384731#:~:text=The%20PSA%20test%20is%20a,below%20the%20bladder%20in%20males.

The Program:

The average amount of Physique 400 taken by fitness and athletic individuals is between 5 to 10 mg per day. You can take it any time throughout the day but to optimize its benefit, take 1 ml (10mg) 30 minutes before training to improve your physical strength and endurance, and accelerate recovery after. This is easily possible because Ligandrol has a half-life of 24 to 36 hrs. Which means it continues to work in your system hours and even days after taking it.

This is also the reason why you need to cycle LGD between 6-8 weeks, take a PCT for 4 weeks before starting again. LGD’s effects kick in after roughly a week. You start noticing you can push more in terms of intensity and volume during your training, you don’t feel as exhausted after a session, and you recover more quickly after an extreme workout routine. Some anecdotes report seeing a physical difference in the body as early as 2 weeks.

Physique 400® is such a potent SARM that it is not surprising to see users gain between 10 to 15 lbs (4.5kg to 6.8kg) from just one cycle when paired with the right muscle-building workout and nutritional calorie intake. For training ideas and proper nutrition tips for your muscle-building goals, read this article.

https://www.elitesarms.com/collections/individual-sarms/products/elite-sarms-re-charge-arimistane-25mg-ml-at-30ml

https://www.elitesarms.com/blogs/news/the-muscle-building-program-to-maximise-your-lean-mass-using-the-elite-sarms-builders

Busting the Myth about LGD-4033

Finally, I would like to address the ‘big fluster’ about Ligandrol causing liver toxicity. There was a reported case, and I would emphasize, one case of increased liver transaminases ‘allegedly’ caused by Ligandrol.

If you look at the study closely, even the authors admitted that:

1. No genetic testing was done to test for hepatic transporter protein abnormalities or other genetic abnormalities that can predispose the patient to drug induced liver injury.

2. They also acknowledged that it is possible that the Ligandrol the patient took had other different unapproved drugs (after all it wasn’t tests conducted with Elite Sarms – Physique 400® 😉

And according to another study, among the 44 products marketed and sold as selective androgen receptor modulators which the researchers have investigated, only 23 (52%) contained 1 or more selective androgen receptor modulators. So you really have to be careful, and smart when choosing your SARMs supplier. (BTW you can see all Elite Sarms Identification and Purity Testing within the images on each Individual Product page. These tests are conducted on each new batch of Elite Sarm individual products before they enter the manufacturing phase).

Which brings me to an important point. If you are going to buy Ligandrol online, it is very important to verify the purity of the product you are going to purchase. Ligandrol is safe to use with the daily dose we recommended—as long as it’s the real deal!!!

One way to know the quality of your SARMs product is to check for the COA (Certificate Of Analysis) done by an independent or 3rd party laboratory, meaning the testing is not conducted by the company selling the product, so no false results can be reproduced and marketed to you. If it’s not posted on the website, don’t be afraid to ask for the Certificate of Analysis. SARMs are research compounds, and it is absolutely your right to verify their purity before you part with your hard earned money.

At Elite Sarms we are proud to display the quality of our ingredients before they even reach our highly qualified medical scientists for manufacturing, as the industry is littered with false products, fakes and scammers and we are here to clean things up, make things right and serve you, the people exactly what you are paying for and not a mg or purity percentage under that.

Train hard, ES.


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304490/

https://pubmed.ncbi.nlm.nih.gov/29183075/

https://www.elitesarms.com/collections/individual-sarms/products/physique-400-lgd4033

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Muscle Building Marvel – RAD140

ES EDM BLOG2

Written by: Michelle G. Thibault
Edited by: Ryan McTeigue

RAD140, popularly known as Elite Sarms TIGHT®, is an investigational compound, which has become popular among bodybuilders, sports people and fitness enthusiasts. When looking to buy SARMs for fat loss and muscle gain, TIGHT® RAD 140 is an easy choice. It is reputed to have muscle-building and strength enhancing effects due to its high affinity with androgen receptors found in skeletal muscles, bones and connective tissues.

For those who are not so familiar with RAD 140, this article highlights the history and discovery of RAD140, and the mechanism behind why it is now considered to be Testosterone’s equal in terms of its anabolic properties – no jokes, this is what the new science is revealing to us.

RAD 140 is a potent, orally bioavailable Androgen Receptor Modulator (SARM) compound that was developed by Radius Health, Inc. It was originally designed as an experimental substance for androgen replacement therapy. Some of the potential benefits of RAD140 being tested within the research studies just to name a few; were for the treatment of conditions such as muscle wasting (cachexia), bone loss, and breast cancer. You can start to build a picture of how this product has come to be one of the most potent muscle building compounds while being non-steroidal.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018048/

https://www.elitesarms.com/collections/individual-sarms/products/tight-rad-140

RAD 140’s Special Features

Tissue selectivity. The tissue selectivity of RAD140 is shown by potent androgen-like properties in bone and muscle, which is mainly anabolic. Studies demonstrated an increase in the weight of the pelvic muscles of castrated rats compared to control groups with RAD140‘s lowest tested dose of 0.1 mg/kg. Impressive!

The physique and sports scene caught on very rapidly to the muscle building effects of RAD 140 making it a popular choice when buying SARMs in USA, Canada and the EU.

However, it demonstrates diminished effects in other androgen-responsive tissues, such as prostate and seminal vesicles – this is a great thing and the reason why it doesn’t cause prostate hypertrophy or infertility.

Particularly, when administered along with testosterone, RAD140 was found to somewhat antagonize the growth effect of testosterone in prostate and seminal vesicles, proposing that RAD140 acts as a competitive Androgen Receptor ligand but with reduced activity. This means that RAD140 successfully competes with Testostorone on AR sites blocking the hormone from attaching to these negative receptor sites, thus inhibiting synthetic testosterones potential tumor-promoting actions on reproductive organs. Tight® therefore, may be effective in use as protection of the prostate and other sensitive reproductive organ sites that high and long doses or testosterone have the potential to negatively effect. Ie RAD140 could be used along-side testosterone to not only enhance the positive effects but to also block any potential negative effects the synthetic testosterone can cause.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083371/


Safety. The same study also found that while taking RAD140, despite the dramatic increases in body weight over such a short time, there was no elevation of liver enzyme transaminase levels in any of the lab mice at any dose >2 fold over its baseline value. Given the established link between oral androgen use and liver stress indicators, researchers were pleasantly surprised that even at a dose 10x greater than the fully effective dose, they saw minimal liver enzyme elevations with RAD140 – this is another very positive finding.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018048/

https://www.elitesarms.com/collections/individual-sarms/products/tight-rad-140

It is Neuroprotective too!

When testosterone levels in men start to fall due to the normal aging process, the risks of dysfunction and disease in androgen-responsive tissues increases, which amazingly, also includes the brain!! After all the brain is a large organ made up of proteins such like any other organ in the body except is carries out a much grander role – allowing us to experience reality.

Since testosterone therapy can cause a potential increase in the risk of developing prostate cancer, scientists have turned to SARMs to overcome these limitations. Studies have discovered that RAD140 lacks significant androgen action in the prostate (the main hardware in the reproductive system) but exerts highly positive effects in selective androgen-responsive tissues including BRAIN NEURONS!

In a 2014 study by the Endocrine Society, RAD140’s effects were investigated in cultured rat neurons and male rat brain. RAD140 was shown to provide neuroprotection, and increased resilience from neurodegenerative diseases.

The study concluded, that by administering RAD140, it activates androgen-protective pathways that reduce cell death induced by 3 factors: Aβ peptides (coming from amyloid deposits seen in Alzheimer’s), apoptosis activator II (seen in tumor and cancer cells), and hydrogen peroxide (produced during cell injury).

Like Testosterone, RAD140 has the ability to protect the brain but also help it to function / perform better. However unlike Testosterone, RAD140 is extremely highly selective, activating androgen receptors in the muscles we use to work out and the brain tissue we use to develop business ideas, and in-general just think and continue being able to think effectively, long into our years.

We here are Elite Sarms believe we are only just looking at the tip of the ice-burg with the muscle building Marvel – RAD140 and we are exciting to continue bringing you research on what the studies continue to reveal about this amazing compound. In the meantime if you would like to conduct your own personal research and see what this amazing compound can do for your physique and for your brain performance, check out Elite Sarms Tight® (RAD140) here.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959610/

https://pubmed.ncbi.nlm.nih.gov/16011741/

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Muscle Building Program to Maximize your Muscle Mass with the Elite Sarms Builders

ES EDM BLOG 819580bd ef14 4d46 ba7f 18ab1de354c6

Written by: M.G. Thibault
Edited by: Ryan McTeigue

There are many advantages to building muscle that go beyond having the perfect body or an increase in physical strength. Whether your desire to consistently train and maintain a particular diet comes from health or aesthetic motivations, for either reason there are 3 main criteria that must be fulfilled to ensure maximum muscle gains occur:

1. Proper nutrition that will support muscle growth

2. An exercise routine that will challenge your muscles and cause stress and adaptation

3. Smart supplementation that will allow faster and full recovery to continue progressing forward

These are just some of the basic foundations for building more muscle than you have right now or at a minimum maintaining what muscle you have right now. To find out more key factors for increasing muscle mass and the factors behind that coveted goal for every male and a growing number of fitness females. For more info and details read on…..


Nutrition

While the topic of Nutrition can spur endless discussions that can go on for days, this article focuses on the importance of protein and some of the major issues that surround this macromolecule. Studies have clearly shown that protein requirements are considerably greater in those who train regularly or play sports.

According to researches published in recent year, in order for muscle protein synthesis (MPS) to take place, a maximum amount between 20 to 40 grams of protein should be ingested per meal. Now, this is a ballpark amount and your requirement may be in the lower or higher limit depending on the frequency and intensity of your physical training.

Another point I’d like to emphasize is Anabolic Resistance. This refers to the body’s decreased ability to absorb amino acids into muscle and is commonly observed in:

  • older adults
  • systemic inflammation
  • insulin resistance
  • disease states

If you belong to one of these groups, what this is implying is that if you are involved in weight-training exercise, you need to ingest a greater amount of protein, particularly essential amino acids, to overcome the Anabolic Resistance effect.

The most important essential amino acid where increased MPS is concerned is the branched-chain amino acid, leucine. Leucine is the trigger amino acid for elevated MPS because it activates the Mammalian Target of Rapamycin (mTOR), kick-starting the entire protein synthesis process. Ideally, to overcome Anabolic Resistance, you need:

2.5 grams of leucine per meal if under 40 years of age, and

4 grams of leucine per meal if 40 years and above

https://jissn.biomedcentral.com/articles/10.1186/s12970-018-0215-1

https://pubmed.ncbi.nlm.nih.gov/29389741/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131552/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848650/

Training

For efficient muscle building effects, you can combine compound exercises to recruit multiple muscle groups at once, with isolation exercises for better form and technique. Train with progressive overload, which means gradually challenge your muscles by increasing the weight or reps performed. This will guarantee bigger gains.

Examples of Compound Exercises (1-5 rep range)

Deadlift

Back Squat

Front Squat

Bench press

Barbell Shoulder press

Clean

Push Press


Examples of Isolation Exercises (10-20 rep range)

Dumbbell Flyes- decline and incline

Cable Crossovers

Bodyweight Flyes

Butterfly Machine

Cable Iron Cross

Cable Flyes- flat bench, incline & decline

Single-Arm Cable Crossover

Low Cable Crossover

Single-Arm Dumbbell Bench Press

Cable Chest Press- incline, decline

Superset 2-4 movements together per set with minimal rest and perform each exercise set twice a week. If you’re reaching the level of muscle fatigue, don’t let your ego get the better of you. If you need to scale back the weight, better listen to your body and avoid injury.


Supplementation:

Whether you are a professional competitor or someone who’s very motivated to refine your physique, you are the kind of in the zone of active muscle building that powerlifters or bodybuilders are working towards. If you are in the fitness scene long enough, you are also aware how supplementation can ramp up your lean muscle gains big time.

Creatine. Creatine is an amino acid found in the body’s muscles and brain. It donates phosphate groups that form Adenosine triphosphate, or ATP. ATP the molecule powering your muscle’s contractions during a workout. Aside from being a phosphate donor, Creatine also serves as a weak buffer preventing the pH within your muscle fibers to drop too low, hence suspending fatigue. In short, Creatine pushes your muscles to work harder and longer.

Recommended dose: To load, take 20 grams of Creatine per day for 5–7 days. For maintenance, take 3–5 grams per day. You can stick with this dosage for a long time.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048496/

Physique 400® (LGD-4033) . Well-known as Ligandrol, it is one of the most researched SARMs because of its potent effects on augmenting muscle mass and volume. When it comes to bulking, Physique 400 is a big leaguer with clinical studies under its belt. It demonstrates powerful hypertrophic effects comparable to anabolic hormones. One major benefit of LGD 4033 is its ability to increase fat-free muscle tissue when bulking.

Recommended dose: 10mg or 1ml of LGD 4033 per day. Suggested cycle length is 6 – 8 weeks.

https://www.elitesarms.com/collections/individual-sarms/products/physique-400-lgd4033

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111291/

Elite Sarms Tight® (RAD 140). More and more studies are comparing RAD 140 as being identical to the anabolic power of Testosterone. In addition to its propensity for muscle building, it amplifies the power and strength of muscle fibers. Seasoned gym goers even stack RAD 140 with Test or prohormones to amplify the effects of testosterone minus the side effects. Almost too good to be true, RAD 140 also shows neuroprotective and regenerative effects on brain neurons!

Recommended dose: 10mg or 1ml of RAD 140 per day. Suggested cycle length is 6 – 8 weeks.

https://www.elitesarms.com/collections/individual-sarms/products/tight-rad-140

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959610/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018048/

Elite Sarms Stanazine® (S4). What makes Stanazine (S4) unique on top of its lean muscle building effects, is its efficacy for increased fat loss and muscle protection during a cutting phase. Because S4 allows you to gain lean mass during intensive training with a limited calorie intake, it is also an ideal supplement for body re-composition.

Other studies compare S4 to the muscle-generating effects of Dihydrotestosterone (DHT), which is 3x more anabolic than testosterone. Stanazine is also proven to boost muscle strength and increase bone mass.

Recommended dose: 25 mg or 1ml of S4 per day. Suggested cycle length is 6 – 8 weeks.

https://www.elitesarms.com/collections/individual-sarms/products/stanazine-s4

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039881/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083371/

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The 411 on Decavar (MK2866) and Hyper Lean (SR9009) for Muscle Hypertrophy & Fat Loss

ES EDM BLOG f8540fb3 b808 4fd0 953d c06394336450

Original Design: M.G. Thibault
Re-design: Ryan McTeigue

In previous Elite Sarms articles, we discussed the different principles involved for muscular growth and development. Resistance training is the key for muscle growth and this component further consists of the following factors:

  • Training frequency
  • Training intensity
  • Training volume

There are different techniques to get maximum muscular growth. Whatever protocol you’re using, it has to satisfy the following requirements for muscle hypertrophy to take place: a combination of mechanical tension and metabolic stress. By finding the optimal balance between these two dynamics, you’ll have an effective hypertrophy-oriented training program and training sessions that will yield maximum results.

Do you wonder why some of the seasoned body builders prefer a high intensity routine, meaning they train almost to the point of muscular failure? According to Jerry Brainum, a noted expert on exercise and nutrition, there are times when the weight will fall out of his hands because of total muscular fatigue. Scientifically and biologically Jerry found he couldn’t do more than 4 to 6 sets per muscle group under such high intensity conditions. Doing so would lead to excess amounts of cortisol released in the body , which leads to muscular break down. He also stated that he made the best gains of his life with those initial high intensity sessions.

https://www.appliedmetabolics.com/4095/achtung-is-german-volume-training-a-better-way-to-build-muscle-by-jerry-brainum/

This factor of high volume, training to failure for increased muscular growth is also supported by a study from the Institute of Sport Sciences in Poland stating that a good foundation for individuals seeking to maximize muscle growth should be hypertrophy-oriented Resistance Training (RT) consisting of multiple sets (3−6) of 6-12 repetitions with varying weight intensities – obviously the higher the weight the lower the repetition range will be.

This 6 – 12 range of repetitions is enough to keep blood circulating around the body and raise blood lactate levels that will stimulate the release of growth hormone to aid in the body’s anabolic activities. While the high intensity level of each set will cause an increase in Nitric oxide levels that leads to vasodilation for better blood supply, over time. Achieving maximum vasodilation also allows your body to rapidly transport metabolized amino acids and nutrients in the tissues. This also means,

↑↑ Vasodilation = greater pumping power = Increase in muscle size

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950543/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794479/

Recomposition or cutting protocol

During a Recomposition or cutting protocol, Resistance Training (RT) volume and intensity is maintained despite a calorie deficit to guarantee that you burn fat while simultaneously building muscle. This is the scientific, physiological and nutritional foundations for body re-composition

In reality, it is hard to maintain your gains when you eat less calories and still maintain your training load. Then there’s the issue of muscle fatigue and injuries that come with attempting to maintain this work load while reducing calories. This is where SARMs supplementation can really help you the most.

The selective androgen receptor modulator, MK 2866, known as Decavar or Ostarine, activates muscle stem cells (satellite cells), which help remodel and regenerate muscles. The implications? This makes Decavar an important tool for efficient recovery post-workout thus preventing muscle fatigue and injuries – assisting in re-composition in times of reduced caloric intake combined with consistent resistant training.

Another cool feature of Decavar is that it increases the activity insulin-like growth factor 1 gene (IGF-1), which boosts muscle growth and strength. Because the half-life of MK-2866 is 24 hrs, taking 1ml a day for a cycle of 6-8 weeks is enough to ensure fat free muscle gains and increased athletic performance.

https://pubmed.ncbi.nlm.nih.gov/26393303/


SR9009, also known as Hyper Lean is another compound that will work synergistically with your Recomposition program. SR9009 sets off a host of processes in the body through the activating and binding of Rev-Erb proteins. This stimulates an increase in the production of mitochondria and oxidative function with an increase in antioxidant activity in the body. This facilitates glucose metabolism for augmented carbohydrate uptake and ultimately lean muscle gains.

Mitochondria are powerhouses of the cells, which enhance metabolism to build your muscle. Even with lesser energy intake during a Recomp, SR9009 helps to synthesize more mitochondria in the muscle tissues leading to an increase in muscle size, and an upsurge in endurance and strength levels improving exercise capacity.

The recommended dose for Hyper Lean® (SR9009) is 1 ml per day either taking once before training or split into an am and pm dosage with around 6 hours between dosages. This 1ml daily dosage is equal to 20mg of active SR9009 in the Elite Sarms range. Hyper Lean has a short half life of roughly 4 to 6 hours. Therefore, to make the most of its fat-burning effects, optimal dosing is twice daily.


https://www.elitesarms.com/collections/individual-sarms/products/hyper-lean-sr9009

https://www.natap.org/2013/HIV/100213_01.htm

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Is it Possible to Gain Muscle Even on a restricted Diet? Discover the Power of S4

ES EDM BLOG d9e71529 dd4f 4018 a3a2 387372cc9d87

Original Design: Michelle G. Thibault
Re-design: Ryan McTeigue

An essential component of effective Body Re-comping is being in a caloric deficit. In reality, it comes down to calories in vs. calories out. You cannot argue against the first law of thermodynamics, your metabolism operates under this universal law. Fat storage will not decrease without the restriction of energy intake.

This has been verified by more than a century of research on nutrition and weight management. Your body burns so much calories in a day and when you provide it with less than the calories it needs, your body has no choice but to utilise fat stores in order to sustain itself.

One of the biggest challenges in a Re-comp protocol is not loosing muscle gains while under a caloric restriction.There has to be a strategy for how much calories are limited, and equally as important – is where those calories come from. It is imperative to eat enough protein so your body can have the raw materials needed to build muscle mass.


Is it possible to Gain muscle even on a restricted diet?

The Answer is YES and thankfully we have science studies to prove it. A 2011 research exhibited that trained athletes were able to gain muscle while losing fat over a 9-week period. This was achieved by performing a slow body fat cut which was equal to a loss of 0.7% of total bodyweight each week (over a 7 day period). Check out the study below for the full report:

https://pubmed.ncbi.nlm.nih.gov/21558571/

How Does Stanazine® (S4) achieve muscle building while on a Calorie Deficit?

S4, more popularly known in the Elite Sarms range as Stanazine® or in the wider sarms world as Andarine, is a selective androgen receptor, known to be among the best SARMs for cutting. In addition to improving muscle gains, S4 is well-established where fat loss is concerned. If you want to have that “dry and lean” physique, it requires developing muscle while having a significant reduction in body fat.

​Stanazine is well known for its muscle protecting abilities. It is ideal during a cutting cycle because you won’t lose hard-earned gains. S4 really is the perfect supplement for a Recomp program which both males and females can use (without vitalising for girls). Research studies showed its ability to strengthen bones and increase lean muscles, even when under a calorie-deficit.

Stanazine® Dosage

This dosage seems to have the best results with almost no side effects. Remember to split your dosing into two parts:

Take 25mg in the morning and 25mg in the evening (for males); that’s 1ml 2x/day.

Take 12.5mg in the morning and 12.5mg in the evening (for females); that’s 1/2 ml 2x/day

The Split dosage protocol is because S4 has a half-life of around 8 hours. Over 99% of a substance is eliminated when seven half-lives have passed. This means a single dose of Stanazine will be completely cleared from your body after 56 hours. Hence, we recommend taking it in small amounts divided over 2 doses, at a cycle length of 6 – 8 weeks.

This protocol will ensure the best results without side effects – the most common side-effect for high dosages of S4 comes from the compounding binding with the AR in the optical nerve of the eyes. This can cause a yellow haze, which is completely temporary and has no long-term negative effect, ceasing when the dose is lowered or completely stopped – but sticking to our dosage protocol will ensure this weird side effect does not occur.

For men who are concerned about Testosterone suppression, don’t worry. At such a low dosage, you will be fine. For women who are thinking of virilisation effects, with 12.5 mg twice a day, it won’t have androgenic effects – just fat shredding ones!

It is important to note that the metabolic rate differs for every person, so you can slowly increase the dose until you find your sweet spot.

Recommended Rep range

The optimal way to keep blood circulating around the body and raise whole-body lactate levels is to pair upper and lower-body exercises for 10-12 reps or in the 12-15 rep range per exercise, with short 30-60 second rest intervals. More lactate corresponds to a greater release of growth hormone, which tells your body to build muscle and burn more body fat.

This will prevent you from losing muscle proteins thereby maintaining the fullness of your gains, and even facilitate lean muscle growth. You can get S4, Stanazine® here


https://www.elitesarms.com/collections/individual-sarms/products/stanazine-s4

https://pubmed.ncbi.nlm.nih.gov/17063395/

https://jpet.aspetjournals.org/content/304/3/1334 https://www.sciencedirect.com/topics/medicine-and-dentistry/elimination-half-life