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Nootropics 101 – How to build a better brain

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Your brain is the main interface between you and your entire universe. How you perceive, respond, and act are the results of intricate biochemical processes that take place inside your brain.

Nootropics have come onto the scene in a big way only in the past 5 years. 10 years ago the word Nootropic would not even be recognised by the average person. But since the movie Limitless came out – everyone opened up to the possibility that there is a compound or a combination of compounds that could allow us to access the other 90% of our brain that is laying dormant – waiting for humanity to bring about the activation of it. Could supplementation and nootropics be the doorway to this happening? Lets find out…

A true nootropic enhances brain function in diverse ways, offering cognitive benefits that stretch far beyond your basic memory pill. Without a doubt, by boosting diverse aspects of the brain’s capacity, true nootropics offer a unique advantage by enhancing virtually every aspect of your life – regardless of who you are, and what you do.

Nootropics have many benefits not only for our brain, but also for the central nervous system as a whole, which the brain is intricately connected to. These compounds boost neurotransmitters, enhance brain energy, improve cerebral circulation, and facilitate the regeneration of neurons.

The question remains, with the plethora of smart supplements flooding today’s market, which of these nootropic compounds afford the most benefit that translate to better mental performance and better overall brain health? Basically, what works and what doesn’t?

This article explores only the research-based advantages of different nootropic agents, and how they can help someone achieve optimum brain performance.


The Top Smart Supplements and how they work

1. Bacopa Monnieri


Bacopa Monnieri – Bacopa was proven effective in easing anxiety while sharpening mental performance minus sedating side effects. This makes Bacopa an ideal supplement for students studying for exams or anyone who needs to pull an all-nighter to beat a deadline. It is a staple memory-booster because it helps slow down the rate at which the brain forgets newly learned knowledge.

https://www.ncbi.nlm.nih.gov/pubmed/23195757 https://pubmed.ncbi.nlm.nih.gov/12093601/

2. Lion’s Mane Mushroom

Lion’s Mane Mushroom – Assists with Nerve Growth Factor (NGF), crucial in brain structure, nerve-protecting myelination and in nerve repair. This mechanism may also explain its clinically shown benefits for bright, balanced mood. This mushroom has neurogenesis-inducing effects , which scientists believe, is associated with its antidepressant and anxiolytic properties.


https://pubmed.ncbi.nlm.nih.gov/23510212/
https://www.jstage.jst.go.jp/article/biomedres/31/4/31_4_231/_pdf

3. Citicoline

Citicoline – One study demonstrated how Citicoline could boost brain energy metabolism by increasing energy reserves and utilization. It is also shown to increase the amount of essential phospholipid membrane components needed to synthesize and maintain cell membranes in the brain. Another research illustrated its neuroprotective effects by accelerating brain regeneration and optimizing brain cell structure.

https://www.ncbi.nlm.nih.gov/pubmed/18816480 https://pubmed.ncbi.nlm.nih.gov/8709678/

4. Rhodiola Rosea 


Rhodiola Rosea – Rhodiola is popularly known to increase brain ATP energy and minimize stress-induced fatigue. Proanthocyanidin, a type of phenolic compound found in the roots of Rhodiola has potent antioxidant activities believed to prevent neuro-inflammation and fight off oxidative stress in the CNS.

http://herbalgram.org/resources/herbclip/issues/bin_554/031645-554/


Multi-tasking Nootropics

If you are the kind of person who seeks to achieve peak physical performance as much as you endeavor in optimizing your brainpower, these cutting-edge supplements will give you the unparalleled benefits you’re looking for:

1. Cardio Shred® Cardarine (GW0742)– It is a PPARδ receptor agonist that mainly stimulates the body’s catabolic pathways experienced during a Cardiovascular workout. It facilitates the breakdown of fat cells, converting them into energy to fuel the body during physical training while using glucose stores to build and develop lean muscles.

Studies in lab mice also demonstrate that Cardarine induces PPARβ/δ activation to alleviate related mental deficits caused by Alzheimer’s disease. This is mediated by increasing fatty acid oxidation in brain astrocytes, which in turn improves cognition.

https://www.elitesarms.com/products/cardarine-gw/
https://pubmed.ncbi.nlm.nih.gov/30453390/


2. TIGHT® (RAD140)– Among athletes and fitness individuals with a main focus on physique building, RAD 140 is a favorite supplement because it has the anabolic properties of testosterone minus the hassles that go hand in hand with roids. One of the most potent Selective Androgen Receptor Modulators (SARMs), it augments lean muscle development without affecting any other androgen sensitive organs outside of muscles, bones and connective tissues.


Having said this, a recent study has shown RAD- 140’s neuroprotective properties in older male subjects, by increasing brain cell growth, and protecting brain nerves against injury from amyloid-beta plaques and other neurotoxins.

https://www.elitesarms.com/products/tight-rad-140
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959610/
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Hacking with Carbs for Better Physique and Performance

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Over the past few years, biohacking has skyrocketed into fame, and has become a trending topic when it comes to body transforming. If you are not familiar with the term biohacking, itis the process of incorporating scientifically proven techniques in a person’s everyday routine to positively effect ones body and biology to look better, feel better and live longer.

For this article, we are going to look closely into Carbohydrates (yes, Carbs!), and we can use this essential nutrient as a biohacking tool to:

1. Improve Athletic performance

2. Increase Energy and Stamina

3. Accelerate Muscle Growth

Believe it or not, with all the buzz that Keto and Paleo diets have received, Carbohydrates still remain as be the best fuel for the body’s engine. The crucial point is knowing the right carbs to take, and the right time to take them for better athletic performance.

FACT: Carbohydrates are the essential energy source during high intensity exercise such as weight training. If you are looking to burn more fat, you still need Carbs to perform your highest facilitate the body’s metabolism of fat molecules for energy.


Carbohydrates and Athletic Performance

Athletes need plenty of carbohydrates before, during and after exercise because it is the fuel that the muscles use when doing any version of short duration, higher intensity work basically anything that isn’t solely cardio that goes for under 1.5 hours. While fats present as an alternative source of energy, the body generates energy mainly from glucose (carbs) to supply energy into the cells particularly during high intensity training.

Have you heard the saying, fats burn in a carbohydrate flame? Simply put, carbohydrates need to be present in order to completely break down fats that will result in the release of energy.


This is the process of how fat is actually burnt during exercise:

Part 1. Pyruvate is formed as a product of glucose metabolism.

Part 2. Fat attaches to pyruvate in the cell’s mitochondria to fire up metabolism.

Part 3. When the body lacks carbohydrates, it turns to muscle tissues as energy source.

So if your diet lacks carbohydrates, the body produces less pyruvate and fat has nowhere to attach to for it to be metabolized, and will halt the body’s fat-burning capacity. If the body is depleted of carbohydrates, critical amino acids are stripped out of protein from muscle tissues to be converted into the body’s fuel. The instant that muscle tissue is decreased, the body’s metabolic rate substantially slows down, and muscle growth and repair is also negatively effected.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050641/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC296885/



Athletes Need Carbohydrates Before, During and After Exercise

Before a training session, ‘top off the tank’ with some low-fat, high-carb foods to help maintain blood sugar during training. A pre-exercise meal serves two purposes for the training athlete:

1. It keeps you from feeling hungry before and during exercise, and

2. It maintains optimal levels of energy for the exercising muscles.

Low-fat and low fiber foods are best to help avoid any stomach upset while foods containing fat and fiber delay digestion time, so they’re best left for consuming after exercise.


During activity, consume 6 to 12 ounces of a sports drink with 6-8% carbohydrate concentration during exercise. Sports drinks are designed to provide much needed fluids and the right amount of carbohydrates to ensure that the muscles receive adequate amounts of energy (about 30-60 grams for the first couple of hours).

Note: Sports drinks should not be confused with “energy” drinks. Sports drinks are beverages that contain electrolytes and carbohydrates and potentially amino acids. Sports drinks contain mainly sugar and artificial stimulant.

After a workout, most of the stored glycogen have been expended and the muscles are craving carbs, so refuelling with carbs is a smart move as they’ll be taken up readily by the muscles and stored away in the muscles for the next workout. Load up on higher fiber carbs post workout along with protein for faster recovery and energy repletion.

https://www.usada.org/athletes/substances/nutrition/carbohydrates-the-master-fuel/



The Best Supplement for Optimum Energy Release

Cardarine (GW-0742) is a great supplement for athletes since it works as a PPAR Receptor Agonist. For those who are not familiar with PPARs, they are transcription nuclear factors found in various tissues of our body and play important roles in metabolic processes, such as regulation of glucose (sugars) uptake into muscle and lipid (fat) breakdown. One study showed that GW0742 has the ability to improve glucose homeostasis in diabetic rats through activation of PPAR-δ.

Another benefit of Cardarine (GW-0742) is that it also regulates cellular metabolic functions which are especially important in fatty acid uptake, transportation, and β-oxidation. These are all key processes to sustain stamina during rigorous physical training, but also vital if you want to shred fat while building muscles. Moreover, as an Exercise-mimetic, researches show that Cardarine can enhance training adaptation or even pre-program the skeletal muscles with Oxidative Fibers to that of a trained athlete. What does this mean?


Oxidative fibers rely on aerobic respiration to fuel muscle contractions, and consist of slow-twitch (Type I) fibers, which are muscles with long contraction duration, and are associated with endurance. Therefore, an increase in this type of muscle fibers essentially means improved physical endurance.

https://www.elitesarms.com/collections/latest/products/cardarine-gw0742/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2393796/
https://www.cell.com/fulltext/S0092-8674(08)00838-6
https://courses.lumenlearning.com/fitness/chapter/types-of-skeletal-muscle-fibers/
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Body Re-comping Secrets You Need To Know (part 1)

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Looking to achieve a sharp and well-defined physique? If you want to get ripped, have rock-hard abs, and the like, you need to be lean all over — usually under 12% body fat if you’re male and below 16% body fat if you’re female (and not pregnant!). And if you’re thinking that countless hours of cardio and hundreds of reps of crunches will do the trick, spoiler alert – It Wont! Lets instead looks into the science of body re-composition, because you know we love science here at Elite Sarms – and no we aren’t talking bro science, we are talking medical publications and physically applied principles by our body research team – training and trialing new systems daily to bring you this practical content. Stay with us on this one, its longer than usual but it’s totally worth it if you want to look your best in 2021 and beyond.

Body recomposition presents unique challenges, but it mainly comes down to how you incorporate the goal into your lifestyle. We are talking about; the right nutrition, an intelligent and sufficient to your goals supplementation program, a consistent training regimen and a focused mind with a clearly defined end-state. This will allow the body to undergo the bio-scientific transformation where it burns fat and builds muscle at the same time – a feat only achievable with the correct training and nutrition principles applied.

This guide will outline a piece of the science, pinpoint common traps, and outline the no-nonsense techniques behind effective Re-comping to help you get started on the right path.


How the Human Body Works

During physical training, the body’s main source of fuel is sourced from muscle glycogen. Glycogen is the carbohydrate stored in skeletal muscle which produces ATP production that powers up your muscles to do the work during physical exercise – in particular, resistance training.

As you training sessions increase in intensity (which should be your goal each training session given you are in full health and full immunity), your muscles utilise the glycogen and generate lactic acid and hydrogen (H+) ions as by-products. When the lactic acid and H+ ions build up, the pH of the blood around the muscles drop creating an acidic environment that prevents the muscles from contracting further. That is what is commonly referred to as ‘reaching failure’, where you have to stop between sets, just enough to allow these by-products to be metabolised.

As you progress with regular training throughout the week, your muscles eventually become depleted of muscle glycogen. Also keep in mind that over time of high intensity exercise and resistance training, your body accumulates cortisol, a hormone that is secreted in response to physical stress. Cortisol is mainly catabolic, meaning it is a muscle-destroying hormone.

Glycogen depletion plus prolonged exposure to excess cortisol levels equals fatigue and muscle loss. If that’s the case, you might think, what’s the use of having a consistent training routine? That’s just half of the story, because it is where the role of Nutrition and Good Supplementation comes into the equation. The reason not everyone who hits the gym can achieve the goal of burning fat and building muscle is because this balancing act of muscle building and muscle breakdown, along with cortisol rising and cortisol falling is always happening throughout each training session with intensity. It’s knowing these factors and balancing them with tact that will help one reach this god-like state 😉


A Tactical Approach

A portion of our daily carbohydrates intake is allotted to the resupply of this muscle glycogen. The question remains: What type of carbs are directed into muscle tissues to be stored as glycogen? And what carbs just contribute to gaining fat?

Remember:

Complex carbohydrates, when ingested and metabolised, gives a much larger ration of glucose molecules to muscle tissues to be stored as glycogen – we are talking sweet potatoes, basmati rice, oats, more examples later.… While simple and refined sugars are absorbed very quickly into the blood stream, with excess amounts being stored into fat cells. Starchy vegetables are great in replenishing glycogen stores because they are not only rich in complex carbohydrates; they also contain a lot of fiber. I will discuss in a minute why this is important.

Complex carbohydrates refer mainly to starchy vegetables such as: Squash, yucca, taro root, and yams. A half-cup (64 grams), cooked serving of any of these veggies offers 15 grams of complex starch carbohydrates. Your digestive tract will quickly convert the starch into glucose to fuel the muscles and subsequently the body, and deposit the rest as glycogen in the muscle just trained.

The high fiber content results in an even slower rise in blood glucose and insulin levels, an effect that can last for hours after eating. Research shows that lower blood insulin levels are associated with greater oxidation of fatty acids during exercise and reduced degradation of muscle glycogen– both important factors in fat burning and muscle building.

It is noteworthy to say that after strenuous exercise that depletes the body’s fuel stores, early intake of carbohydrate is essential because it provides an immediate source of replenishment to the muscle, while also taking advantage of the increased insulin sensitivity to drive the carbs into skeletal muscle. If you were to have a daily cheat meal – scientifically speaking directly after an intense resistance training session would be the best time to have it, as the muscles are hanging for a source of carbohydrate to replenish the used up glycogen, a simple sugar will supply that need very fast and effectively, just don’t go overboard or you’ll store the extra sugar as fat! You’ll have to experiment with your own body to find your perfect post-workout carb feed to know what is best for YOU!

https://pubmed.ncbi.nlm.nih.gov/10776896/
https://pubmed.ncbi.nlm.nih.gov/22095115/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019055/

The big challenge in Body Re-comping is the individual requires a restricted or calorie-deficit diet to induce a fat-burning state, while sustaining the body’s strength and conditioning for a consistent workout routine and capacity to gain muscle mass. Unless one goes on a calorie maintenance daily intake and uses a product such as Decavar (MK2866), Stanazine (S4) or Hyper Lean (SR9009) – these are all great Re-composition tools to put in your supplement arsenal to be successful in your re-composition mission.


Optimising Advanced Scientific Supplementation

If you find it tough to eat below your daily caloric requirement, maximising the benefits of proper supplementation may just be your lifesaver as far as re-comping goes.

These supplements will not only facilitate fat loss, they are also designed toward directing glucose particles to fuel and develop muscle tissues instead of your food intake being converted into fat deposits. Cardarine GW-0742 is a PPAR-δ agonist, which regulates fat oxidation, ultimately used in gluconeogenesis, which in turn promotes skeletal muscle growth.

Supplements that improve Insulin Sensitivity are a vital component in the body transformation mission. Magnesium is a proven natural insulin sensitizer, efficiently improving insulin sensitivity and glucose tolerance. Alpha Lipoic Acid is another supplement to further research for insulin sensitisation. ALA is an important antioxidant that lowers triglyceride (fat) accumulation in skeletal muscle by activating AMPK to optimize insulin function and enhance nutrient storage.

Another factor to focus on for body recomping is to increase your metabolic rate by facilitating the pathways the body use to burn calories. Supplements such as Hyperlean SR9009 prevents the storage of fat tissue by improving glucose and fatty acid oxidation to support skeletal muscle development. This REV-ERB α and β agonist fires up your metabolic rate to break down fatty deposits while simultaneously increasing lean muscle bulk. And this peoples is part I of Body Re-composition and direct application into your lifestyle regime. Take it onboard and physically apply it, or don’t either way you now know Part I of Elite Sarms re-comping science.


Stay tuned for next weeks conclusion about the story of your body…….

https://www.elitesarms.com/collections/individual-sarms/products/cardarine-gw0742
https://care.diabetesjournals.org/content/26/4/1147
https://pubmed.ncbi.nlm.nih.gov/15913551/
https://www.elitesarms.com/collections/individual-sarms/products/hyper-lean-sr9009
https://www.ncbi.nlm.nih.gov/pubmed/22460951
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085709/

In part 2 of this article, we will explore:

1. The Art and Science of Carb Cycling

2. Carb Cycling on Motivation and Other Benefits

3. How to Use your Cheat Meals to Burn fat

4. The 2-type Carbohydrate Protocol

5. Exercise Intensity and Volume during a Recomp

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Elite Sarms Guide to High Level Athletic Performance

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Aside from your basic abilities in agility, strength, control, and endurance, if you want to take your athletic performance to the next level, having a solid plan that incorporates training, nutrition, supplementation and recovery is required in order for you to be a healthier, fitter and stronger athlete. Becoming a high performing athlete doesn’t happen by accident. It takes some planning.

Moreover, you need an easy to follow program to gain the most competitive edge when it comes to you versus you.

If you desire to master your particular sport, physique or physical endeavor has landed you here right now, then read on… Our simple Intel tips may just be the answer to help you go that next level you’ve been seeking to hit and truly excel athletically. 

Training Habits You Can Adopt from Professional Athletes

Schedule Training sessions 3 or More per Week

To be the best you, why not follow some of the protocol of your favorite athletes. You’re a professional or semi-pro, it is understandable to train every day because it is kinda your job. If you fall under organizational or recreational sports, however, take a page from the experts by training at least 3x a week. This creates good habits for strategic training, allowing you to master your moves, challenge various body parts in different sessions, while giving them ample rest and recovery time.

Improve your Mental Toughness

Pro-athletes have the ability to dig deep, so they can push through mental barriers that impede performance whether they’re on training or when competing. There are many techniques you can try depending on your preference. You can try NLP [Neuro-linguistic programming], Self-talk, Hypnosis or even hire a mental coach! Whichever you end up using, study findings  show that psychological resilience have protective factors on athletic individuals in withstanding the pressures  and stressors that they experience during training and competition.

https://pubmed.ncbi.nlm.nih.gov/24716648/

Avoid Training Too Hard Too Often

Current fitness programs have latched on all things HIIT. While high intensity workout sessions serve a purpose on your training plan, it cannot be your sole focus. Athletes can employ high-intensity training periodically to improve cardiovascular function, but not too often since it can go the opposite way and increase injury risk and raise stress hormone levels.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988244/

Nutrition Advice to Increase Your Competitive Edge

Strategic Carb Loading

Stop seeing carbs are the enemy and start using carbs to your advantage. Did you know that every person you see right now on Instagram that you believe looks in top shape eat carbs. They have to to fuel their muscle because muscle actually has around 70% of carbs stored within them the rest being up from proteins such as connective tissue, bone mineral, blood and cellular material. The difference is, they know when to take them and what kinds will yield them the greatest athletic performance or physique results. Carbs are an athlete’s main fuel. Period. Your body changes them to glucose, and stores it in your muscles as glycogen. During training, your muscles convert glycogen into energy. According to Sports dietitian Joy Dubost, PhDCarbohydrate loading for 3 or 4 days before an athletic event can help top up your glycogen stores. Reload on carbohydrates after intensive exercise, too. Since you don’t need quick energy, it’s best to choose complex carbohydrates like veggies and whole grains.

https://www.webmd.com/fitness-exercise/features/nutrition-tips-athletes#1

Optimize your Protein Intake

Energy and protein needs vary depending on the intensity and frequency of athletic training. The US and Canadian Dietetic Association  recommend 1.2 to 1.7 grams of protein per kilogram of body weight per day for athletes, depending on training. Protein intake should be spaced throughout the day and consumed after workouts to accelerate muscle repair. 

https://pubmed.ncbi.nlm.nih.gov/23107527/

Hydrate, hydrate, hydrate

Intense exercise, especially in hot weather, can quickly leave you dehydrated. Lack of fluids, in turn, can hurt your performance and, in extreme cases, threaten your life. Restoring fluids maintains normal muscle function, helps prevent a decline in physical performance and reduces the risk of heat stress.

The Effects of Hydration on Athletic Performance

Top Supplements for Your Competitive Edge

Creatine

Athletes, pro and leisure alike, are familiar with the effects of Creatine as a nutritional aid for sports performance. Red meat and seafood are rich in Creatine, but it is also available as a supplement.Studies demonstrate that supplementing with creatine can increase muscle mass and improve strength when a person combines it with strength training.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407788/

Ashwagandha

Ashwagandha is an Ayurvedic herb, widely popular as an adrenal tonic and testosterone booster. An effective adaptogenic, A 2015 study has proven the herb’s  augmenting effects on endurance in healthy athletic men and women.Subjects who received the root extract showed a significant increase in physical endurance after 8 and 12 weeks of treatment compared to the control group.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687242/

Cardio Shred® (GW0742)

Cardio Shred® (GW0742) stimulates the biochemical pathways initiated when a person undergoes a cardiovascular workout. A Peroxisome proliferator-activated receptor (PPAR) agonist, Cardio Shred breaks down fats and utilize fatty acids to fuel the body, power up the mitochondria of muscle fibers, thus enhancing physical endurance and delaying exhaustion.

Researches show that PPARs have a positive association with the potential to achieve elite status in human physical performance in strength and power, team, and aerobic sports.  Specific agonists like Cardio Shred® (GW0742) activate these genes, and may bring a beneficial effect to achieving maximum sports status.

https://www.elitesarms.com/collections/athletic-performance/products/cardarine-gw0742

https://pubmed.ncbi.nlm.nih.gov/31881714/ Pro-Tips on Athletic Recovery

Cryotherapy. Have you watched a video of an athlete diving into an ice bath? It’s not some kind of spoof, athletes do it for real!  It may look horrible, but they actually make it to accelerate their recovery to allow them to train harder and faster sooner. Cryotherapy chambers operate at -110°C to -190°C temperatures, which sports and fitness buffs expose themselves to for just a few minutes. This helps them recover from the day’s rigorous training session –including a reduction of systemic inflammation and lowering concentrations of markers for muscle cell damage.

https://pubmed.ncbi.nlm.nih.gov/29161748/

Contrast Water Therapy

Contrast bath therapy comprises alternating cycles of submerging in very warm water and very cold water. The body’s exposure to changing intervals of extreme temperature stimulates the contraction and dilation of the blood vessels and stimulates the body’s circulation.

Lab studies found that contrast bath therapy may help reduce muscle soreness post-workout, facilitating to offset the negative effects of strenuous exercise. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633882/
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RAD 140 – Testosterone and Muscle Building

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Testosterone levels usually peak around adolescence and early adulthood. During this period, gains in muscle mass and strength are easy and at their optimum potential. You may have a full mane of thick, luscious hair, a nonstop sex drive and a relentless motivation that can take on anything you put your mind to.

But, as we age, our hormone levels steadily decline which typically starts around 30 years old. As you begin to notice the changes that become more apparent with growing older, you begin searching for ways to hold onto the aptitude and youthful vitality you once had. But exactly what are the signs and symptoms to be aware of for when testosterone levels begin to drop? And is it possible to avoid these symptoms and delay the effects of ageing hormone levels?

Continue reading to find out…


Countless studies have been conducted in the pursuit of reversing the ageing process. And while scientists search for effective modalities to achieve perpetual youth, the signs and symptoms of ageing remain to be the same. Typical changes that occur as a result of diminishing hormones and in particular the decline of testosterone include:

1. Physical changes. This includes a reduction in muscle bulk and strength, increased body fat, and decreased bone density. Lowered energy and stamina. Swollen or tender breasts otherwise known as – gynecomastia and hair loss.

2. Changes in sexual function. A relevant decrease in sexual desire, fewer spontaneous erections, and infertility can eventuate.

3. Altered Moods. Diminishing testosterone can also lead to a drop in motivation, and a drop in self-esteem. Lack of focus and trouble remembering things. And irritable and/or depressed moods.

https://www.ncbi.nlm.nih.gov/books/NBK216175/#ddd00036

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422548/


If you’ve been looking around at the anti-aging industry in hopes of dodging the perils of dropping test levels, you may be familiar with testosterone therapy. You may have heard it’s reported benefits of renewed strength and instant vitality. It may seem common sense – if testosterone drops as you age, just replace it with the hormone itself. While Testosterone Replacement Therapy (TRT) sounds promising, it is equally vital to know the risks also.

According to an article by Mayo Clinic, Testosterone therapy has various risks, including:

For many, the decrease in testicle size and weight and the complete shut down of natural testosterone production usually steers regular gym goers away from testosterone and its derivatives. But what if there was a compound that could offer the benefits of testosterone without shutting down natural test and keeping testical size and weight the same??? Enter RAD140.

https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/testosterone-therapy/art-20045728
https://www.ncbi.nlm.nih.gov/pubmed/27132578

RAD 140: The future of Androgen therapy?

So far, you’ve learned the importance of Testosterone and its impact on man’s physiology. You’ve also been shown that while TRT may help reverse the effects of male ageism, there is solid proof that recipients of this modality are susceptible to serious side effects also.

Fortunately, there’s a new class of investigational compounds called selective androgen receptor modulators, or SARMs, which have the same benefits of the testosterone hormone WITHOUT the side effects. These novel compounds are highly selective and only interact with the androgen receptors of muscles, bones and other connective tissues of the musculoskeletal system. This explains why SARMs don’t have any adverse effects on the liver, prostate, heart and organs that are likely to suffer when using synthetic anabolics.

RAD140, also known as Testolone or Tight® in the Elite Sarms range, has fast become a favorite among bodybuilders, athletes and biohackers because it is one of the strongest SARMs up to date and is comparative to the strong anabolic effects of testosterone and dihydrotestosterone (DHT) when it comes to increasing muscle mass.

It is now being used as an alternative to hormone replacement therapy in men with low testosterone levels, without the hazards for developing benign prostatic hypertrophy or accelerating the progression of existing prostate cancer.


We have established the anabolic, energy- promoting and anti-aging impacts of RAD-140 and how they’re almost identical to testosterone. What is also exceptional about this compound is that because of its impressive safety profile, some synthetic anabolic users will stack RAD 140 with smaller amounts of testosterone to reinforce the effects of testosterone without the side effects.

Lastly, we need to note RAD140’s amazing neuroprotective properties. In older male subjects, cognitive decline was shown to be associated with diminished testosterone circulating in the blood. This is supported by studies that exhibit testosterone’s important role in protecting the brain. Testosterone and RAD140 can increase brain cell growth, improve memory, and decrease amyloid-beta build-up. Please note that Amyloid-beta plaques are among the main causes of Alzheimer’s disease. In a separate study, RAD140 protected brain nerves against injury from amyloid-beta plaques. Additionally, RAD140 and testosterone were equally effective at protecting against neurotoxins.

To find out more about RAD140 known as Tight® in the Elite Sarms range you can check it out here. Thank you for reading 🙂


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018048/

https://www.elitesarms.com/products/tight-rad-140
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907129/

http://onlinelibrary.wiley.com/doi/10.1002/rcm.6558/full

https://www.ncbi.nlm.nih.gov/pubmed/24428527
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959610/
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How S4 Stanazine can Increase your Athletic Power

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Many sports individuals and professional athletes maximize their nutrition and employ supplements to enhance their performance. Whether you are looking to advance your game or aiming to take home the cup, at the end of the day you want to improve, and feel great about your physical fitness and development. Well, there is on Sarm that is an excellent performer in both Athletic Performance plus increasing strength and power. That Sarm is S4 known in the Elite Sarms range as Stanazine®.

No doubt, the sports and fitness industry is flooded by thousands of supplements that make all types of claims and this can be confusing and overwhelming. Admissibly, there are many effective and decent supplements in the market, but in this article I want to put the spotlight on the novel compound S4 Stanazine to show you how this supplement is miles ahead of the game in terms of sports performance, fat cutting, crazy muscle pumps and drastic power increases and how S4 delivers all of this. This article talks about how it’s easily one of the closest compounds to the “perfect tonic” to jack-up your game performance.

The advent of Selective Androgen Receptor Modulators or SARMs has been phenomenal, particularly in the world of fitness and sports. SARMs certainly raised the bar when it comes to safe, effective and accessible supplements for physique and sports enhancement

Developed by GTX, Inc under its then brand name, Andarine, S4 Stanazine was originally conceptualized as a safer alternative to anabolic steroids for the treatment of muscle wasting diseases and Osteoporosis. If you are familiar with SARMs compounds, S4 like the other sarms has excellent binding and activation to the body’s androgen receptors, and therefore mimics the effects of testosterone minus the usual side effects of synthetic testosterone. 

https://en.wikipedia.org/wiki/Gtx_inc
https://www.elitesarms.com/collections/athletic-performance/products/stanazine-s4

How can S4 (Stanazine®) help athletes amp their competitive edge?

We just don’t babble about unfounded claims here. At Elite Sarms, our Intel lets the Science do the talking… 

Bone Density

The health of the skeletal system is important for athletes young and old. If there is a disruption in the equilibrium between bone formation and resorption, bone stress injuries and fractures can occur. This will surely set back your fitness advancement, especially if this happens over a spectrum of repetitive mechanical stresses during training and gaming events. Keeping the bones strong and powerful will mean you stay injury free and continue to advance past your competitors, who aren’t taking direct action to ensure their bones are in the best possible conditions for all the stress you are putting them under during training and competition. 

Studies on ovariectomized female rats (a female rat whose ovaries have been removed) show that S4 administration increased bone mineral density and strength in the trial subjects, while also improving muscle strength. This means even without the life force of a female mammal removed, the subject continued to increase in bone mineral strength and muscle strength – this is no small finding, especially the effect this would have on healthy subjects.  

The studies imply that the incidence of fracture can be reduced through Stanazine’s dual mechanisms: one, via direct effects in bone strength and quality, and two, by decreasing the incidence of falls as stability is supported with increased muscle strength.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349390/
https://pubmed.ncbi.nlm.nih.gov/17063395/

Muscle Mass

According to the National Strength and Conditioning Association,  fitness components such as agility, power, coordination, etc., rely on body and in particular muscle composition to a large extent. An increase in lean body mass contributes to strength and power development. And muscle size and quality is positively related to Strength and power. 

In one study, castrated male rats received S4 for four weeks and ended up with higher muscle weight, similar to the effects of dihydrotestosterone (DHT). 

What this means for the athlete, is that with regular dosing of S4 Stanazine, lean muscle gains are achieved. It follows that by increasing lean body mass, the athlete is able to generate more force in a shorter period of time. Than without daily dosing of S4 for a period of time (we recommend 12 weeks of continual for S4, before taking a break to let the Androgen receptors regain their sensitivity for greater gains in the next supplementation cycle. Greater muscular strength

According to sports scientists and practitioners, muscle strength is directly associated with improved force-time characteristics that influence an athlete’s overall performance. Numerous research studies support the opinion that greater muscular strength can enhance the capacity to execute general sport skills such as jumping, sprinting, and quick change of direction movements.

https://www.nsca.com/education/articles/kinetic-select/sport-performance-and-body-composition/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039881/
https://pubmed.ncbi.nlm.nih.gov/26838985/

S4 Stanazine 5:2 dosage Protocol

A dose of 25mg per day for 5 days on and 2 days off per week is recommended. Each bottle contains 30 days of use. 1 ml is measured on the included glass dropper and is equivalent to 25 mg. 

Cycle Length: 8–12 weeks.

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Elite SARMS – non-toxic sports supplements

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We have uncovered the latest and most effective non-toxic sports supplements which have taken the US and AUS market by storm; SARMS. The name SARMS stands for ‘Selective Androgen Receptor Modulators’ – For many reasons, this product is quite simply one of the greatest discoveries in the fitness industry to date.

Elite Sarms Info

The key point being that they are selective, meaning they specifically target the muscles, body fat, bone and connective tissue with no conversion to estrogen, meaning they are perfect for athletes looking to take their body and performance to the next level.

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Protect® (Tamoxifen): Combatting Estrogen Dominance for Effective Fat Loss

By: M. G. Thibault

Hormones regulate many bodily functions in women, including sleep, stress, appetite, and libido, to name a few. It may be overwhelming to fully comprehend the hormone puzzle, and we are here to help you better understand how hormones work and how they can affect our bodies and health. Estrogen and progesterone are two of the most important hormones affecting women.

Estrogen is a female sex hormone and its primary function is to promote growth. It is especially important during puberty and pregnancy, and it plays a role in the menstrual cycle, bone strength, and fat distribution in the body.

Progesterone is a hormone secreted by the female reproductive system to regulate the uterine inner lining (endometrium), and plays an essential role in regulating the menstrual cycle and maintaining the early stages of pregnancy.

What is Estrogen Dominance?

Estrogen dominance occurs when there is an excess of estrogen in the body relative to other sex hormones. Estrogen dominance can cause abnormal menstruation (heavy/painful periods), fluid retention, headaches, decreased sex drive, bloating, mood swings, fatigue, anxiety & depression, breast tenderness, and hormonal weight gain. If you are experiencing some of these symptoms, excess estrogen is a big possibility. Let’s investigate further to know what’s causing this and how you can manage disproportionate levels of estrogen.

Factors Contributing to Estrogen Dominance

Insulin and cortisol imbalance: These two hormones regulate stress responses and blood sugar levels in the body, which can interfere with ovarian, thyroid, progesterone, testosterone, and sleep hormones.

Contraceptive Pills: The pill controls your hormones by preventing ovulation. However, if you do not ovulate, you do not produce progesterone, which can result in higher estrogen levels.

Poor liver function: estrogen is detoxified by the liver and then eliminated through the bowel. If our livers aren’t working properly and we’re not getting rid of the estrogen, it can lead to a buildup.

Weight gain: Because our fat cells can produce estrogen, the more fat we store, the higher our estrogen levels can rise.

Poor diet: To effectively metabolize estrogen, the body requires B vitamins, magnesium, zinc, omega-3 fatty acids, and protein. If you don’t get enough of these vitamins and minerals in your diet, your estrogen levels will rise.

Family genetics: Also play a role in estrogen production. Some women may produce too much estrogen without any negative symptoms, whereas others struggle greatly.

Chemical estrogens: ingested or absorbed through the skin, chemical estrogens such as BPA, pesticides, and beauty products can mimic our bodies’ own estrogen, causing levels to rise.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222987/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689796/
https://pubmed.ncbi.nlm.nih.gov/15050110/

Managing Estrogen Dominance:

Liver support: avoiding substances toxic to the liver, particularly alcohol, in order to efficiently metabolize estrogen and facilitate its elimination.

Reduce your stress levels: to help balance your cortisol levels.

Manage insulin levels: by eating a diet low in processed sugar and carbohydrates.

Avoid chemical estrogens: by using BPA-free plastics or alternatives, switching to natural brands for toiletries and cosmetics, and going organic to reduce pesticide exposure.

Lose weight: remember less fat = less estrogen production.

Supplementation: we recommend taking supplements to help restore balance between your estrogen and progesterone levels.

Protect® (Tamoxifen) in Reducing the Effects of Estrogen Dominance

We talked about the use of supplements to facilitate a healthy estrogen balance and one of the most effective products currently available is Protect® (Tamoxifen). Classed as a selective estrogen receptor modulator or SERM, it is a non-steroidal anti-estrogen drug developed in the 1960’s to prevent breast cancer. By blocking the effects of estrogen in the body, it stops the proliferative effects caused by the hormone in certain cancers. Although initially used to treat breast cancer patients, it has gained popularity among fitness people and bodybuilders as a fat loss agent. The benefits of using tamoxifen to burn fat with minimal muscle wastage has made it popular as a fat burning agent in both healthcare and the fitness industry.

While Protect® (Tamoxifen) doesn’t directly promote weight loss, it can prevent estrogen-induced weight gain. Tamoxifen can help minimize the amount of receptors available for estrogen binding. Because of this, you’ll be less likely to add weight and you’ll have a better chance of losing stubborn fat around problem areas like the stomach, hips, thighs and triceps.

Upon binding to estrogen receptors, tamoxifen blocks the action of estrogen and significantly reduces the accumulation of adipose tissues. This is extremely important because as we mentioned, fat gain can be caused by high levels of estrogen in the body. By binding with these receptors, Protect® effectively inhibits these effects.

In a ground-breaking study, published in The Journal of the American Medical Association, researchers found that tamoxifen was proven to increase muscle mass and reduce body fat percentage in both men and women. Furthermore, the use of tamoxifen
is associated with improved cardiovascular health, which helps increase blood flow and aids in recovery from strenuous exercise.

If you are concerned about safety, it is important to note that SERMs don’t actually eliminate the estrogenic compounds in the body, meaning the risk of low estrogen related problems are severely reduced. Protect® does not carry the risk of totally eliminating a women’s estrogen, opening her up to joint and reproductive issues as well as a greater risk of virilization

For dosing recommendations, the typical dose for breast cancer patients is around 20-40 mg a day. You don’t need to take that much. Off-label use of Protect® (Tamoxifen) as a fat shredding agent is 10-20 mg a day, which is equivalent to .5-1ml daily.

Conclusion

If you want to burn body fat and get ripped more efficiently, give tamoxifen a try. This drug blocks the effects of excessive estrogen in your body, and exerts a direct effect on your body’s ability to lose stubborn body fat while preserving lean muscle mass. Protect® (Tamoxifen)  is fairly safe since it allows women to enjoy the physique benefits of a reduced estrogenic load without actually removing the estrogen, which is then free to perform other body functions.

https://www.elitesarms.com/products/elite-sarms-protect-tamoxifen-20mg-ml
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669751/
https://ajp.amjpathol.org/article/S0002-9440(17)30780-0/fulltext

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The A,B,C’s of Sarms in Getting Bigger and Stronger Muscles

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By: M. G. Thibault

Mechanism of anabolic hormones in muscle

What are Androgenic Receptors?

You probably already know that testosterone and synthetic esters of this male hormone have a huge role in muscle growth and development. However, do you know the exact role of androgenic receptors (AR’s) in muscle growth?

Androgenic receptors are the primary target of anabolic steroids, growth hormone, IGF-1, and most performance-enhancing drugs work by stimulating hypertrophy in muscle tissues. 

There is a considerable density of androgen receptors in muscle tissue, specifically in the myonuclei. These receptors profoundly modulate the response of the muscles to contractile stimuli (ie. Resistance training – weights). The data indicates that the androgenic receptors are critical regulators of muscle growth, being both necessary and sufficient for full stimulation of protein synthesis and for fiber growth inside the muscle.

Because there are more testosterone-receptor proteins than actual cellular androgen receptors, this shows that there is a biological mechanism within all cells to respond whenever it encounters androgens.

Given AR’s widespread expression in many cells and tissues, Androgen receptors have a diverse range of biological actions including important roles in the development and maintenance of the reproductive, musculoskeletal, cardiovascular, immune, neural and hemopoietic systems.

https://www.researchgate.net/figure/Mechanisms-of-action-of-anabolic-hormones-on-skeletal-muscles-AR-androgen-receptor-UPS_fig2_264432884
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2439518/
https://elitebioscience.co/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810760/

Many of today’s bodybuilders, athletes, and fitness enthusiasts are taking supplements daily in order to improve some aspect of their physique. These compounds are usually synthetic anabolic or growth promoting agents that work by artificially increasing hormone levels and the secondary to that – stimulating the androgen receptor sites, which in turn allows for the development of the muscle cell with increases in strength depending upon the compound used. Sarms bypass the artificial hormone elevations and drops and targets the Androgen Receptors directly and selectively.  

Androgenic Anabolic Steroids

When you hear about anabolic steroids, you think about their ability to increase muscle mass and strength. However, what many people don’t know is that these compounds also come with some severe side effects on a user’s health, due to their non-discriminatory action on different cells. 

As what was mentioned earlier, androgen receptors are found in different cells and tissues all over the human body. They are present in fat tissues, muscles, bones, the prostate gland, liver, nervous system, brain, hair follicles and cardiac cells.  

So when you say non-discriminatory action, this means that when you take testosterone for muscle growth, it doesn’t only stimulate the androgen receptors in the skeletal muscles, it also affects the different AR’s in the body resulting in oily skin, acne, hair loss, headache, nausea and vomiting. What’s even worse, some individuals take massive amounts of this testosterone esters that are way, way above the recommended dose, which may cause, in extreme cases, liver diseases, prostate cancer and heart attacks. As soon as a synthetic hormone enters the body, it signals the hypothalamus in the brain to stop producing LH and FSH. In short, natural testosterone production is shut down as the body reads there is no reason to continue producing T since it is receiving synthetic testosterone from and outside source. Sarms mitigate this process by their design of not being a hormone, but a direct Androgen Receptor Modulator.

https://www.webmd.com/drugs/2/drug-5185/testosterone-cypionate-intramuscular/details

Selective Androgen Receptor Modulators (SARMs)

Mechanism of SARMS

This is where Selective Androgen Receptor Modulators (SARMs) come into play. These compounds have a selective action on the body, which means that they affect only certain parts of it. SARMs are a novel class of androgen receptor ligands. They bind to the androgen receptor more selectively, exhibit tissue selective activation of gene transcription and enhance protein synthesis. The relative selectivity of SARMs for muscle and bone over prostate and sebaceous glands has potential application in the treatment of muscle wasting, osteoporosis and functional limitations associated with aging. 

The unique pharmacology of SARMs makes it a much safer choice compared to androgenic anabolic steroids. Because of its high selectivity — meaning it only stimulates the androgen receptors of muscles, bones, body fat, nerves, connective tissues and in some Sarms like Tight® (RAD140), the brain. Sarms have become a reliable tool and a fitness staple among serious fitness enthusiasts, bodybuilders and athletes who aim to take their physique and strength building goals to the next level.

With Elite Sarms Tight® (RAD140), a daily intake of 10mg, which is equal to 1ml, affects muscle tissues resulting in a significant increase in strength and endurance. By attaching to androgen receptors, Tight® (RAD140) stimulates muscle development while repairing connective tissues (bones and joints) and efficiently metabolizing body fat.  

Another muscle building superstar in this category of compounds is Elite Sarms Decavar® (MK-2866).  Decavar® (MK-2866) stimulates tissue regeneration by targeting the androgen receptors in muscle fibers. It also increases nitrogen in the blood vessels that supply muscle tissues, enabling more blood and nutrients to flow and nourish the muscles. The enhanced levels of nitric oxide also improves and aids in muscle tissue recovery by clearing lactic acid and sustaining pH balance, thus making Ostarine the greatest muscle tissue regenerator of all SARMs.

Decavar® (MK-2866) has been demonstrated in studies to prevent muscle degradation following recovery from major surgery or other disorders.

HOME | ELITE SARMS GLOBAL | #1 WORLDWIDE
https://www.elitesarms.com/products/tight-rad-140
https://www.elitesarms.com/products/decavar-mk2866

What is The Take Home?

Overall, what we’re trying to achieve is to get as close to the ideal scenario as possible. And that means not only getting the proper nutrition and training with enough volume and intensity, but also choosing a healthy and intelligent supplement regimen in a way that favors muscle growth.

SARMs are a class of supplements that offer similar anabolic effects to steroids with the purpose of increasing muscle mass, gaining strength and promoting the loss of fat without the undesirable side effects associated with steroid use. Rest assured, with appropriate dosing of your chosen SARMs supplements, trusted suppliers with full transparency (See ES Lab Tests Results here), you will not experience water retention, blood pressure increase, liver damage or testosterone shutdown, while enjoying the benefits of maximum gains in lean muscle and strength while preserving your hard earned muscle.

Elite Sarms are the future of athletic performance supplementation. 

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Our Testosterone Boosting Secrets

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Testosterone is vital to a person’s overall health and well-being. Low levels of testosterone, due to aging or a medical disorder, can negatively affect body composition, slow down metabolism, decrease libido, and cause mood depressions. 

If you are experiencing symptoms of suboptimal testosterone levels, or want to boost it simply because it can improve your mood and motivation, accelerate healing and enhance your body-building efforts, this article is for you.

Diet Rich in Fatty Fish

Fatty fish like salmon, pilchard, mackerel, and sardines are rich in nutrients that are important for hormonal health. Aside from Omega-3 fatty acids, they are also packed with vitamin D and zinc.

While high cholesterol and fried foods are linked to decreased testosterone levels in some people, research showed that low-fat diets can also be detrimental for test stores. In a 2016 study,  DHA-rich fish oil sourced from fatty fish increased testosterone synthesis in male subjects after only 12 weeks of supplementation. Another study showed that zinc, when supplemented with magnesium, has contributed to elevating serum testosterone in varsity football players. 

In a different study, a significant increase in total testosterone levels, bioactive, and free testosterone was observed in the vitamin D supplemented group compared to control subjects.

https://pubmed.ncbi.nlm.nih.gov/33741447/
https://pubmed.ncbi.nlm.nih.gov/33221700/
https://www.asep.org/asep/asep/BrillaV2.PDF
https://pubmed.ncbi.nlm.nih.gov/21154195/

Resistance and Strength Training

Resistance exercises are proven by research to cause an acute surge in serum testosterone while augmenting long-term levels. Resistance training, such as weightlifting, is a great exercise to boost testosterone, particularly in male athletes. A 2007 study found that non-athlete male university students who did strength/resistance training 3 days a week for 4 weeks were linked to increases in T levels right after a workout and over time. 


To boost your T levels, perform 2-3 sets of 5-8 reps at 95 percent of your maximum effort, targeting larger muscle groups like the quadriceps, hamstrings, back and chest. Follow by strengthening smaller muscle groups, like your biceps, calves and shoulders to help prevent injury and speeds up your metabolism. Next we reveal the Elite Sarms products that work to create Testosterone and HGH cycle effects…..

https://www.ncbi.nlm.nih.gov/pubmed/17051372

RAD 140

A type of selective androgen receptor modulators, or SARMs, it has the same benefits of testosterone WITHOUT the side effects. This exciting new compound is highly selective and only interacts with the androgen receptors of muscles, bones and other connective tissues of the musculoskeletal system.

You might wonder why I included RAD140 on the list when there are no investigations linking it to Test synthesis. Popularly known as Tight, while it doesn’t increase T levels, RAD 140 is commonly stacked with other prohormones or steroids in the market to reinforce the effects of testosterone without significant side effects. According to research, it is a Testosterone amplifier, which enhances your natural hormone’s biological action.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018048/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907129/
https://www.elitesarms.com/products/tight-rad-140
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959610/

HGH Optimization

Scientists are now investigating the potential of Human Growth Hormone (HGH) as a prospective treatment for low testosterone. This theory is fast gaining traction among health and fitness sites and anti-aging clinics.

HGH, a hormone secreted by the pituitary gland, is secreted into the bloodstream to regulate various biochemical processes in the body. With the advent of hormone therapy clinics, monitored injections of HGH can help people with a growth hormone deficiency, sports injuries, or decreasing levels of HGH because of aging to improve bone density, build muscle mass, reduce body fat and speed up the repair of damaged tissues.

Based on another study, growth hormone works like a gonadotropin, a hormone that stimulates the activity of the gonads to secrete sex hormones. According to clinical results, HGH administration stimulated testosterone as well as estradiol secretions by Leydig cells in lab rats. It also modulates the action of T3 and LH to augment secretion of these steroids.

https://pubmed.ncbi.nlm.nih.gov/10943734/