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Posted on April 1, 2022September 26, 2023 by ryan — Leave a comment

Growth Hormone Hacking Through Scientific Workouts

Science has unlocked major discoveries in the way we can improve our overall health and longevity. But for many, understanding how to use these scientific breakthroughs to sustain a healthy mind and body is a daunting task.

This year’s anti-aging toolkit comprises of 3 different aspects:

Holistic nutrition- Go the extra mile by including foods in your diet that help combat free radicals by targeting DNA repair and cell renewal.

Targeted training- Integrate workouts to improve fitness levels, maintain cardiovascular health, and boost metabolism.

Smart Supplementation- Take the appropriate supplements that will maximize your body’s capacity for tissue regeneration and proper organ function.

Youth-preserving diet

You could live more than a decade longer by eating more plant-based foods. That’s according to a new study from the University of Bergen in Norway that was published today in PLOS Medicine.

A 2020 analysis found that eating whole grains, vegetables, fruits, nuts, and coffee is associated with a reduced risk for all-cause mortality. A high intake of red or processed meats was associated with higher all-cause mortality.

The benefits of consuming unsaturated fats and oils include improved blood cholesterol levels and reduced heart disease risk. The American Heart Association recommends that instead of saturated or trans fats, use olive oil in salads and cooking, canola oil when baking, or sunflower oil for frying.

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003889

https://pubmed.ncbi.nlm.nih.gov/31631676/

https://www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia/the-skinny-on-fats

Age-reversing workouts

You can help protect your cells from aging with regular exercise. A new study published in the European Heart Journal found that High intensity interval training (HIIT) and Endurance training increase telomerase activity, which is beneficial for cell growth and replication. Telomeres are nucleotide sequences found at the end of chromosomes that protect our genetic information. They allow cells to divide, replenish, and reproduce. When they shorten, cellular aging occurs. HIIT and endurance training were found to increase telomere length, inhibiting cell death, and ultimately producing an anti-aging effect.

A great way to find the right intensity of your workouts is through the HIIT method. Research has shown that many people are able to stay engaged with HIIT workouts because they get to choose their own intervals and work-to-recovery ratio. Below is a sample progression of work-to-recovery HIIT ratio that you can make up to 4 rounds.

Week 1-4: Ratio of 1:3. Example, 30 seconds work: 90 seconds recovery

Week 5-8: Ratio of 1:2. Example, 30 seconds work: 60 seconds recovery

Week 9-12: Ratio of 1:1. Example, 45 seconds work: 45 seconds recovery

Week 13-16: Ratio of 2:1. Example, 90 seconds work: 45 seconds recovery

HIIT Workouts: Sit-ups. Crunches. Push-ups. Cable chops. High knees. Jumping jacks. Lunges. Squats. Chest press. Sprints.

Endurance Sports: Cycling. Triathlons. Swimming. Rowing. Tennis. Boxing. Field Hockey. Long distance running. Cross-country skiing. Martial Arts.

https://academic.oup.com/eurheartj/article/40/1/34/5193508

https://pubmed.ncbi.nlm.nih.gov/18391173/

https://www.topendsports.com/fitness/top-sport-endurance.htm

The Best Anti-Aging Supplements

GH Pep (MK-677) enhances your own body’s secretion of Growth hormone, essentially disrupting the undesirable effects of aging. It’s like turning back the clock by years! Also discovered to release more IGF-1, a.k.a. the key to anabolic lean tissue growth and mediator of metabolic homeostasis, (MK-677) maximizes the biochemical pathways of your body to achieve optimum energy, vitality, and extend your mental and physical peak.

The Biotropin HGH Pen is the perfect low dose solution for those who want to enjoy the benefits of Human Growth Hormone: Increase lean body mass and accelerate fat loss; Improve muscle strength and reduce muscle fatigue; Promote collagen production and wound repair; Reduce wrinkles, repair skin elasticity & improve skin texture.

ELITE SARMS GH Pep (MK-677) is one of the most potent Growth Hormone (GH) secretagogues in the market, which effectively boosts the pituitary gland’s GH secretion. Together with its partner, the Elite Bioscience Biotropin HGH Pen, your body’s Growth Hormone level is accelerated to new heights!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5488279/

https://journals.sagepub.com/doi/abs/10.1177/0363546520920591?journalCode=ajsb

https://www.elitesarms.com/collections/individual-sarms/products/gh-pep-mk677

https://www.scielo.br/scielo.php?pid=S0365-05962011000600015&script=sci_arttext&tlng=en#nota

https://elitebioscience.co/

https://pubmed.ncbi.nlm.nih.gov/10984252/

https://pubmed.ncbi.nlm.nih.gov/10352397/

Posted on March 16, 2022September 26, 2023 by Jordan Pearce — Leave a comment

Fat Loss Blockbusters: Elite Fat Loss Guide 2023

OG Design: Michelle Gabata-Thibault
Edited: Ryan McTeigue

It’s that time of year where everyone seems to focus on getting their fitness and weight loss programs on track. With the Holiday season over, along with cheat days and ‘understandable’ lapses in training and dietary protocols, now is the best time to update your body goals and get your new re-composition routine cracking.

At Elite Sarms we have a few clever hacks and foolproof tips to support your fat loss journey in 2022.

Fast Burn Tip #1- Tweak your Habits to Facilitate Weight Loss

While you can’t wish your way to a trimmer waist or wave a wand to make extra body fat disappear, slowly tweaking your habits to work for you can be “the trick”. Swapping your light soda habit for lemon water may be just what you need to stop bloating and cleanse your organs to help your liver metabolise fat easier. Working on the 5^th floor of your company building? Hit the stairs and burn more calories instead of using the elevator. And instead of surfing on your phone during commercials while you’re watching TV, you can have a quick HIIT workout for 4-5 minutes instead. Small consistent tweaks pay big dividends over time.

https://www.medicalnewstoday.com/articles/318662

Fast Burn Tip #2- Eat more seafood

Crustaceans such as crabs, shrimp, crayfish and lobsters are rich in the mineral zinc which ramps up leptin production, which reduces food intake and body weight.

Fish is a substantial source of minerals, such as iron, that sends oxygen to our muscles to burn a sufficient amount of fat for fuel; magnesium, also in seafood is essential for metabolism and energy production; and iodine, helps reverse a slow metabolism by producing more thyroid hormones.

https://pubmed.ncbi.nlm.nih.gov/17028377/

https://pubmed.ncbi.nlm.nih.gov/20846876/

https://www.medicalnewstoday.com/articles/322644/

https://pubmed.ncbi.nlm.nih.gov/18279014/

Fast Burn Tip #3- Give your Jaw a workout

If you want to boost your calorie burn, you need your jaw muscles to be working. There’s more to chewing your food than what your Mom told you so. Mastication increases ‘diet-induced thermogenesis’–energy expenditure- while improving blood-sugar control. What’s the goal? Aim for 40 chews per mouthful, instead of the typical 15. You’ll less likely to have second helpings due to increased oral stimuli including the duration of tasting food in the mouth for longer along with the extra duration of chewing your food.

https://www.nature.com/articles/s41598-021-03109-x

Fast Burn Tip #4- Applying Technology to your Fat Loss Routine

Technology is already a big part of everyday life. It makes sense that it can be just as helpful as a fat-shredding tool. There are so many cool products and free health apps out there to facilitate your journey. Fitness and activity devices track your steps, heart rate, weight and body fat%, sleep and so much more. If your like us, we will sit in front of the computer for long periods every day, you can set your phone alarm hourly as a reminder to stretch, or do those 5-minutes of burpees 🤮

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407266/

Fast Burn Tip #5- Choose the Right Supplements to Maximize Fat Loss

SR9009, popularly known as Hyper Lean is a novel compound that will supercharge your metabolic capacity. SR9009 binds to your Rev-Erb proteins to activate fat and glucose metabolism. By increasing the production and function of your muscle tissue’s mitochondria, it facilitates nutrient uptake, leading to muscle fiber hypertrophy, and an increase in endurance and strength levels that definitely enhances exercise capacity.

Recommended dose is 1ml daily which is equal to 20mg. Hyper Lean has a short half life of roughly 4 to 6 hours. To make the most of its fat-burning effects, the ideal dose is twice daily, which can be split into 0.5ml – 1ml each dose.

Check out Hyper Lean® in our ES – Lean Endurance Stack here

https://www.elitesarms.com/products/hyper-lean-sr9009

https://www.natap.org/2013/HIV/100213_01.htm

Posted on January 27, 2022September 26, 2023 by Jordan Pearce — Leave a comment

Hormones and How they Affect Body Fat Loss

Hormones are biochemical messengers secreted by endocrine glands to control the different processes in your body, especially your metabolic pathways. If you are having difficulty losing weight or simply looking to shed fat, understanding your hormones and working with them can help you take your fat loss to the next level.

In this article, we will review the major hormones that affect the accumulation of adipose tissue and the metabolism of fat, which are vital to your body transformation journey. By improving the efficacy of your hormone profile, homeostasis is reached, leading to better fat loss. Read on for understanding of how this works.

Leptin and Leptin Resistance

Synthesized by fat cells, the hormone leptin is secreted into the bloodstream to reduce a person’s appetite and control how the body stores adipose tissues. This means that if you have a higher body fat percentage, your leptin levels are higher. You get to think, okay, if I have a higher amount of leptin, that means lesser cravings because it is an appetite suppressant.

The problem is with higher amounts of this hormone, its sensitivity is also greatly reduced. As a result, you don’t feel full during and after a meal… Which eventually leads to over-eating and weight gain.

Solution: Regular physical exercise, sufficient sleep, a decrease in sugar consumption are helpful steps you can adopt to improve leptin sensitivity.

Insulin Regulates Fat metabolism

Insulin holds a major role in regulating carbohydrates and fat metabolism. Where lipid metabolism is concerned, insulin decreases the rate of lipolysis in adipose tissue while stimulating fatty acid synthesis and uptake of triglycerides from the blood, leading to fat accumulation.

Insulin resistance is very rampant today due to hereditary predisposition, stressful lifestyles, diet, and environmental factors. This leads to hyperinsulinemia because your body doesn’t respond to the effects of insulin. This eventually results in the abnormal accumulation of fat tissues in the body and the development of metabolic disorders.

Solution: GW0742, a selective peroxisome proliferator-activated receptor (PPAR)-δ agonist, has been shown to improve metabolic abnormalities including Insulin Resistance in skeletal muscle of lab mice. 1ml a day of Elite Sarms Cardio Shred® Cardarine (GW0742) maximizes your body’s fat burning capacity as it increases glucose uptake to fuel up your muscles and stimulate lean mass gains.

https://pubmed.ncbi.nlm.nih.gov/21864752/

https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/expert-answers/hyperinsulinemia/faq-20058488

https://www.elitesarms.com/products/cardarine-gw0742

https://pubmed.ncbi.nlm.nih.gov/26508837/

Human Growth Hormone (HGH) Speeds up Lipolysis

Human Growth Hormone (HGH) also called Somatotropin, is anabolic, particularly for your bones and muscles. What’s unique about HGH is that it has an opposite effect on fats, by stimulating the breakdown and oxidation of adipocytes.

The most immediate effect of growth hormone (GH) administration in humans is a significant increase in free fatty acids after 1-2 hours, reflecting the stimulation of lipolysis and ketogenesis. The insulin-antagonistic effects of GH help in shredding fat stores in the body while simultaneously building lean muscle and bone density.

Solution: Optimize your HGH levels to easily burn excess fat, including those stubborn lumps that cling to your body despite your regular workouts. Biotropin® HGH stimulates lipolysis, a process for burning adipose tissues, thus promoting weight loss. Biotropin® HGH also stimulates hormone-sensitive lipase (HSL) enzyme to facilitate fat cell breakdown by releasing it from adipose tissues, resulting in a significant reduction of body fat.

https://pubmed.ncbi.nlm.nih.gov/12914720/

https://pubmed.ncbi.nlm.nih.gov/1861630/

Androgens Decreases Fat Buildup

Androgens have a negative effect on adipogenesis and lipid synthesis by up-regulating the Androgen Receptors for catecholamine, thus increasing lipolysis. In addition, androgens reduce lipoprotein lipase (LPL) activity that is necessary for fat accumulation. By inhibiting the LPL enzyme, it also stops adipose tissue from building up on skeletal muscles and organs.

Solution: LGD4033 (Physique 400®) is one of the best SARMs for muscle-building and fat loss. Thanks to its potency that equals androgenic hormones like Testosterone and DH, Physique 400® increases fat loss while growing lean muscles, affecting no other organs because of the high selectivity of its effects mainly confined to your bones, skeletal muscles and connective tissues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770848/

https://www.elitesarms.com/collections/individual-sarms/products/physique-400-lgd4033

Posted on November 10, 2021September 26, 2023 by Jordan Pearce — Leave a comment

Anti-Aging Biohacks for Athletes of Any Age

By: M.G. Thibault. Edited by Ryan McTeigue

Whether you are in your 20’s or whether you are in your 50’s it doesn’t matter. The following hacks below won’t just make you feel younger, they will help your body regenerate, recover and for the ladies there is even some beauty biohacking thrown in here. These trends in Age-reversal and body amplificationcome and go especially with new scientific discoveries and advancements in medicine.

However, the best way to find out which modality is right for you is through careful research and professional consultation so you can discuss your goals and customize a hormone and cellular enhancing program tailored to your lifestyle, genetics, needs, and budget.

Here are the most promising non-invasive anti-aging treatments and devices predicted to go big according to our Intel’s forecast.

Infrared Sauna

Infrared Sauna. Scientists at Stanford-Burnham Prebys Institute confirms that sauna use have beneficial effects on health and longevity. What happens is when you expose the body to high temperatures of about 120°-180° F, it creates heat shock proteins and stimulates the lymph system, which detoxifies the system and increases microcirculation. Far Infrared saunas (FIR) are waves of energy, entirely invisible to the naked eye, which infiltrate the surface of the skin where they slightly elevate the body’s surface temperature. FIR are shown to reduce inflammation and oxidative damage, and has the potential to alleviate health conditions that arise with aging.

https://www.sciencedaily.com/releases/2017/02/170215084050.htm

https://www.hightechhealth.com/longevity-benefits/

Stem Cell Facelift. This revolutionary treatment provides the regenerative benefits of stem cell therapy for anti-aging purposes, but entails no surgery and no downtime. A new study finds that after just a few weeks, stem cell treatment eliminates the skin’s sun-damaged elastin network, and replaced with normal, undamaged tissues.

Basically, stem cells migrate to sites of inflammation to dramatically calm down the inflammatory cascade and then lay down a new cellular framework. This treatment yields dramatic skin renewal and a natural lift that can last 3 years.

https://www.sciencedaily.com/releases/2020/05/200528160510.htm

https://journals.lww.com/plasreconsurg/Abstract/2020/06000/Photoaged_Skin_Therapy_with_Adipose_Derived_Stem.12.aspx

Endermologie

Endermologie. Endermologie is a noninvasive mechanical body-contouring used in the treatment of cellulites. Here the cellulite-affected skin is sucked between the rollers and kneaded for approximately 34-45 min. Endermologie was initially developed in the late 1970s in France to soften scars and standardize physical therapy; however, other benefits were seen in patients treated with the LPG machinesuch as improvement in body contour and skin texture, reducing the appearance of cellulite and retaining the youthful suppleness of the body.

https://www.tandfonline.com/doi/abs/10.1080/14764170510037761

https://pubmed.ncbi.nlm.nih.gov/9502849/

Bioidentical Hormone Replacement Therapy

Bioidentical Hormone Replacement Therapy. Bioidentical hormone replacement therapy (BHRT) is a popular modality when it comes to effectively treating hot flashes, mood swings, low libido, and a decline in energy- all of which are symptoms that accompany aging.

Our production of certain hormones begins to decrease as early as our mid 30’s. As one gets older, this decrease in certain hormones changes the way cells and tissues function leading to a myriad of uncomfortable symptoms. BHRT is also a reliable treatment for osteoporosis, thinning hair, poor memory, and other forms of chronic inflammation, that may be observed in both men and women.

BHRT helps correct hormonal deficiencies by providing the body with hormones that have the exact same chemical and molecular structure as those endogenously produced by the body. BHRT is a perfect example of how rejuvenation treatments can help clients age more gracefully and painlessly. BHRT has gotten a lot of attention in recent years as they promise a “natural” solution to hormone issues. One example is Biotropin® HGH synthesized via recombinant technology, which has the exact protein structure of your natural growth hormone, and is made up of 191-amino acids.

A Biotropin® HGH replenishment course boosts Somatropin levels and effectively stimulates tissue repair, cell renewal, and sustain brain and other organ functions thus alleviating the typical symptoms that come with ageing.

https://www.healthline.com/health/bioidentical-hormone-replacement-therapy

https://www.onlinebiologynotes.com/production-human-growth-hormone-hgh-recombinant-dna-technology/

Posted on October 28, 2021September 26, 2023 by Jordan Pearce — Leave a comment

Circadian Rhythm and Rejuvenation. How Re-Setting The Rhythm Can Potentiate Your Entire Body

By: M.G. Thibault. Edited Ryan McTeigue

Your Circadian rhythm controls many aspects of your health from sleep to heart rate, hormone secretion, blood pressure, neurological function, and metabolic routes. As you can see many things which can either improve of decrease an athletes performance.

Today, researchers are learning that the circadian rhythm can also be a new target to help rejuvenate the whole body and extend lifespan. This area of research holds so much potential that lab studies from MIT discovered a link between a healthy circadian rhythm and the constant rejuvenation of an organism. Scientists are positive that by enhancing the body’s circadian cycle, one can prevent and treat diseases not only due to aging but disorders that arise from very active (fitness lovers) or strenuous lifestyles (most humans on earth).

You can’t really exaggerate the importance of this research since many health conditions arise from the disruption of our circadian rhythms especially in these modern times. These increasing disturbances in one’s “body clock” is strongly linked with inflammatory states including neurodegenerative diseases.

Whether disorders in the body arise from stressful daily routines, environmental toxins, excessive physical demand, or simply from aging, at the molecular level, thanks to our scientific community, a person can now restore the body’s circadian rhythm to a more youthful state and effect complete rejuvenation in the body.

https://news.mit.edu/2013/the-link-between-circadian-rhythms-and-aging-0620

https://pubmed.ncbi.nlm.nih.gov/27885006/

Based on the ongoing stream of confirmatory data, there are particular compounds that can help synchronize and restore the proper operation of the body’s circadian rhythm. This article will prove to be of great value if you feel out-of-sync with your current sleeping habits. This article is for the following person who is:

– Consistently working out

– Regularly engaging in sports or outdoor activities

– Involved in mentally demanding tasks as part of the job

– Constantly multi-tasks in a daily basis

– Looking to increase their productivity levels

– Gearing up for a more challenging workload ahead

– Experiencing problems due to inflammatory conditions

– Already feeling age-related effects in performance

If one of more factors on this list describe YOU, your priority right now is to regain control over the proper function of your circadian rhythm in order to re-claim your essential health and rejuvenate your body to its highest level. Below we outline a few hacks which can greatly help with this task::

1. Melatonin

Scientists have found that we can keep our circadian clock in sync through melatonin supplementation. This unique nutritional approach targets both central and peripheral clocks to regulate circadian rhythm. When the brain’s pineal gland secretes melatonin, this helps normalize hormone production, neurotransmitter functions and healthy sleep patterns.

A 2017 study shows that daily supplementation of 10 mg of Melatonin in subjects with obesity decreased oxidative stress and facilitated body weight reduction while improving the body’s antioxidant defence. This factor translates to healthy, normal individuals as well.

https://pubmed.ncbi.nlm.nih.gov/25287733/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632922/

2. SIRT 1 activators

Researchers have shown that SIRT1 (Sirtuin) helps regulate circadian rhythm and protect against the diseases of aging. The SIRT1 gene is also shown to protect against diseases of aging and plays a key role in controlling the body’s circadian rhythms. Conversely, loss of SIRT1 function impairs circadian control in young mice, mimicking what happens in normal aging. Activating the SIRT1 pathway to sustain adequate circadian control and thus reverse aging is a probable therapeutic target that Regenerative Medicine is currently looking into.

By activating the SIRT1 pathway, damage in our DNA created by environmental factors, stress, energy deprivation, and toxins that the body accumulates are constantly being replenished and cell division continues to ensue.

Sirtuin-activating compounds include ginseng, resveratrol, quercetin, polyphenols found in bitter vegetables, cacao, curcumin, ginger, and DHA sourced from fatty fish, eggs, and algae. So ensure you add greens to your daily meals and consider into adding the aforementioned herbal and food supplements into your weekly routine – test it out and see if you feel better after at least 14 days of consistent usage.

https://pubmed.ncbi.nlm.nih.gov/32084459/

3.Rev-erb-α Agonists

Rev-erb-α is critical for the proper timing of the core clock machinery, regulating many metabolic functions, which include lipid and bile acid metabolism, gluconeogenesis, and the body’s inflammatory response. Rev-erb-α ligands, specifically agonists or activators, modify the transcriptional activity (telling the body what to do) and suggest that Rev-erb-α may serve as a promising target for the treatment of circadian alterations of metabolic pathways.

Rev-erb-α modulation was proven to be efficient in phase-advance sleep disorders commonly seen in the aging population, while it helps correct delayed circadian rhythms, frequently seen in individuals with super-active or very stressful lifestyles. In short compounds such as SR9009 can help to balance the circadian rhythms in both sleep deprived and overly-active individuals – assisting in rejuvenation and regeneration of the entire body. Leading to more energy to train, work and do more of the things you love doing!

Rev-Erbα agonists such as Hyper Lean SR9009 has been proposed to coordinate circadian metabolic responses while maintaining the timely schedule of wakefulness, sleep, body temperature, and hormone regulation which in turn facilitates a myriad of biochemical pathways. Therefore, Rev-erb-α ligands may be useful in resetting the Circadian clock into its youthful resonance and efficiency.

You can find Elite Sarms Rev-erb-α Agonist Hyper Lean® (SR9009) here.

Sweet dreams,

-ES

https://www.elitesarms.com/collections/individual-sarms/products/hyper-lean-sr9009

https://journals.physiology.org/doi/full/10.1152/japplphysiol.00570.2009

Posted on October 20, 2021September 26, 2023 by Jordan Pearce — Leave a comment

Diverse Rejuvenation in a Bottle – Decavar MK-2866

By: M.G. Thibault. Edited: Ryan McTeigue

While scientists continue and progress in SARMs research, studies are increasingly assessing how to push the boundaries of SARMs development to maximize their potency, bioavailability, half-life and tissue selectivity, while minimizing side effects. Over 50 years of androgen research has resulted to one of the most cutting-edge SARM – MK-2866 (Decavar®).

MK-2866, otherwise known as Ostarine or Decavar® is a compound developed by the company Gtx Inc. In 2009, initially designed to fight muscle wasting diseases like cancers in all forms. MK-2866 went through numerous phases of trials from roughly 2005 through 2014. MK-2866 was studied and tested for its effectiveness against different medical conditions. It has a molar mass of 389.33g/mol and its melting point is 270°F to 277°F or 132°C to 136°C, rendering its stability even at higher temperatures, scientifically MK2866 is a sturdy compound.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907129/

https://www.elitesarms.com/collections/individual-sarms/products/decavar-mk2866

Pharmacodynamics of MK-2866

MK-2866 is an orally available non-steroidal SARM (all Sarms are non-steroidal despite having steroid like results, an amazing fact in and of itself) that has shown promising results in both preclinical and clinical trials, and is currently being studied for a number of different indications.

MK-2866, popularly known as Decavar is a selective androgen receptor modulator, which aims to increase the growth of muscle mass and improve strength. This main action occurring through the drastic increase of repair and rejuvenation of collagen. Collagen being the material located throughout the body in: muscle, bone, tendons, ligaments, organs, blood vessels, skin, intestinal lining and all other connective tissue. It’s this collagen increase and modulation of repair that attributes to Ostarines muscle building, muscle and joint rejuvenation, muscle conditioning and strength increasing properties. The compound also prevents muscle wasting that occurs in diseased states, fasted states and accompanies aging.

What is MK-2866’s mechanism of action?

MK 2866 is highly selective and only binds to bone and muscle androgen receptors while simultaneously modulating collagen as previously mentioned. What is so impressive about this novel substance is that it has multi-functional properties and the product can be used for not only building muscle mass, but for the regeneration of joints, muscles, and connective tissues. The substance proves to be a great bone regenerating supplement fortifying bones and prominently enhancing the strength and density of them. Structural improvements in post-menopausal female subjects were proven in lab testing resulting in bone improvements such as increased bone mineral density and increased bone volume density. You can then imagine the bone fortifying results a trained athlete will receive when the application of MK2866 is introduced to their training regime.

A 2019 study in the University of Life Science researched the effect of MK-2866 on fat cells of lab rats. The research results demonstrated:

The stimulation of androgen receptor expression. Whereby the metabolism was improved by facilitating the mRNA and protein expression of Androgen Receptors.

Decavar MK-2866 stimulates lipolysis. Investigations found that as little as 1 μM (micromole) of MK-2866, roused lipolysis in isolated rat adipocytes (fat cells) after just 120 and 480 minutes of incubation.

MK-2866 inhibits lipogenesis (fat creation). In animal studies MK-2866 displayed a marked effect on the halting of glucose (carbohydrates) to lipids (fats) in the lab. When MK-2866 is added to animal adipocytes (fat cells), it also inhibited (ceased or reduced) the rate of fat creation in those test subjects.

Decavar MK-2866 modulates the expression and secretion of leptin. Leptin is a hormone that sits in the stomach lining and basically tells the brain when you are full. When this signal is disrupted one will continue to eat beyond the bodies energy requirements – and disrupted leptin levels are the culprit of these signals to the brain telling one to eat more.

Leptin levels being low or disrupted (usually via consuming inflammatory creating foods) are directly associated with adipose tissue mass (fat tissue mass). Leptin concentrations are directly connected to cases such as obesity and cardiovascular diseases such as hypertension and myocardial infarction, both of which are more commonly seen in the aging population. Experiments showed that by administering MK-2866 to isolated rat adipocytes, leptin gene expression was normalised.

https://pubmed.ncbi.nlm.nih.gov/29785666/

http://www.jpp.krakow.pl/journal/archive/08_19/pdf/10.26402/jpp.2019.4.04.pdf

https://www.elitesarms.com/collections/individual-sarms/products/decavar-mk2866

Dosing

Most MK-2866 cycles last between 8 and 12 weeks. The cycle for beginners on average begins with a lower dosage of 10mg. With more experience in the use of SARMs, the dose can be increased, but the entire cycle should not last more than 12 weeks.

Decavar® is highly anabolic especially when paired with a well-calculated balanced diet including adequate, quality protein, good fats and complex carbs. Leaving the weekends or set days to eat outside these healthy foods and replenish the inner child through “cheat meal”. Then jumping straight back onto the horse and riding the nutrient rich diet once again. For us normal to serious training folk a good nutrition split is 80/20; 80% clean nutrition with 20% for not so clean, not so nutrient dense cheat meals. But that’s a whole other blog…….

Future Trends

The research community is now looking on esterification of MK-2866, a process in which the compound is altered to increase the half-life and biological action of the compound. So Instead of taking 1 dosage of Decavar® daily this could lead to only having to take 3, 2 or 1 dosages in a weekly period. Although this process is in the early experimental stages, the pharmacological optimization of one of the most documented and widely used SARMs – Decavar® (MK2866) offers a fresh take and may open up more exciting avenues for SARMs research.

Posted on October 7, 2021September 26, 2023 by Jordan Pearce — Leave a comment

Elite Sarms Rejuvenation Biohacking Tech

By: M.G. Thibault Edited by Ryan McTeigue

Aging leads to a series of changes in an organism as deep as the cellular level. Although, the mechanisms that underlie aging are poorly understood, innovations in science continue to identify factors that explain the decline in fitness and the rise of different health problems that go with advancing age.

While slowing the aging process remains to be a popular topic, what’s even more compelling is the subject of Age-reversal; this is referred to as Rejuvenation.

Rejuvenation is a process that not only defers aging, but literally reverts it- resulting in a younger cell, tissue, or body. Rejuvenation includes diminishing all the damages your body has accumulated throughout its lifespan, and erasing the hallmarks of a matured age. Come to think of it, successful rejuvenation not only leads to the extension of life but ultimately to eternal youth! Does it look like something you’d be interested in? Read on…

https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.13483

Cell-regenerating Nutrition

Our body is an extraordinary machine and its primary fuel are the nutrients we get from the food we eat on a daily basis. By purposefully consuming foods that have ‘supercharging compounds’, a person can promote the rapid regeneration and restoration of some of the body’s most important tissues and organs.

Nerve-regenerative substances:
A 2010 study published in the journal Rejuvenation Research, for instance, found a combination of blueberry, green tea and carnosine have neuritogenic (i.e. promoting neuronal regeneration) and stem-cell regenerative effects in an animal model of neurodegenerative disease. Other researched neuritogenic substances include: curcumin, Lion’s Mane Mushroom, and apigenin, a plant flavonoid usually found in celery.

On the other hand, you can stimulate liver mass regeneration and function by ingesting via supplements that focus on liver renewal such as Korean Ginseng, Rooibos, Vitamin E, and Carvacrol, a compound found in oregano.

https://pubmed.ncbi.nlm.nih.gov/20586644/

http://www.thehealersjournal.com/2014/09/25/how-to-regenerate-your-bodys-cells-with-food-and-herbs/

https://pubmed.ncbi.nlm.nih.gov/24266378/

https://pubmed.ncbi.nlm.nih.gov/30949912/

Age-defying Exercises

According to a medical article, exercise improves muscle health by renewing the powerhouse of the cells: the mitochondria. Mitochondria are vital to the proper functioning of our bodies, and the improvement of our overall health and longevity.

Aerobic exercise, in particular, positively affects the mitochondria through a process called “mitophagy.” Mitophagy is a mechanism by which damaged or defective mitochondria are selected and removed, usually after a period of stress. This keeps skeletal muscle healthy and strong by improving the mitochondrial quality of the muscle fibers.

If you are a gym person- the treadmill, elliptical or rowing machine may be your go to equipment to achieve your fill of cardio exercises. Likewise, if you prefer the outdoors, you may try swimming, soccer, triathlons and cross country skiing as enjoyable alternatives to improve your aerobic capacity.

https://www.medicalnewstoday.com/articles/319532#Exercise-promotes-mitophagy-in-mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630798/

Supplements for Age-Reversal

In the ever-evolving world of Cellular rejuvenation, supplements are constantly being discovered and re-formulated. So far, the following are considered to be on top of the food chain when it comes to reverting the aging process:

There are secretagogues, which stimulates the endocrine glands’ ability to secrete more Growth Hormone, which in turn affects the major metabolic pathways in the body, such as fat oxidation, glucose utilization, muscle synthesis, and collagen production just to name a few.

Rejuvenation procedures in private clinics almost always integrate bio-identical Somatropin injections as part of their hormone optimization courses, while others employ drips and infusions of high doses of Vitamin C to regenerate hormones that have degraded. A powerful electron donor, vitamin C has the capacity to provide electrons in order to resurrect the form and function of estradiol, progesterone, and testosterone.

https://www.elitesarms.com/collections/anti-aging/products/gh-pep-mk677

https://www.healthline.com/health/vitamin-c-injection

Current Modalities on Rejuvenation

Ablative laser resurfacing is generally considered to be the gold standard for the rejuvenation of facial photo-damage and scarring. The procedure is a wounding laser that gets rid of the thin outer layer of skin (epidermis) and heats the underlying skin (dermis), which then triggers the growth of new collagen fibers. As the epidermis heals and regrows, the treated area appears smoother and tighter.

Neck rejuvenation mainly targets skin laxity, that often increase with age due to progressive loss of bone mass, increased subcutaneous fat, and loosening of the connective tissue framework. Using unipolar and bipolar radiofrequency or Infra-red light, sagging skin in the neck area is targeted yielding a tighter, firmer, and younger looking skin just after a few sessions.

A new paradigm for human cell rejuvenation, cellular reprogramming proves to be a promising route when it comes to retracting the procession of aging, which is the basis of rejuvenation.

This is the most recent breakthrough in the anti-aging field, which involves a genetic or chemical method to reverse the epigenetic age of cells. This genetic code instructs mature, specialized cells to read the right genes at the right time, as though they were young again. The factors scientists are currently using to reprogram these mature cells are called Yamanaka factors, which can turn back an adult cell into a young, pluripotent stem cell. Literally!

https://www.mayoclinic.org/tests-procedures/laser-resurfacing/about/pac-20385114

https://www.researchgate.net/publication/225927112_Treatment_of_Neck_Laxity_with_Radiofrequency_and_Infrared_Light

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960911/

Posted on September 22, 2021September 26, 2023 by Jordan Pearce — Leave a comment

BioHacking Your Way To Your Best Physique  - An Elite Sarms Future Supps Adventure –

By: M.G. Thibault Edited by Ryan McTeigue

It is true that you can’t increase the time and effort required to create your greatest physique ever, however you can maximize your efforts and go above and beyond traditional training programs to achieve a lean, strong and greatly developed physique, in comparison to the average person. In this article, we will discuss advanced supplement protocols and advanced training techniques that work in synergy so you can improve your overall workout productivity and move toward your best body achievement.

The following are the latest biohacking techniques that will allow you to achieve fitness, fat loss, and clean gains in minimum time using new discoveries about human biology, physiology and access to modern technology.

Glucagon-Like Peptide 1

Glucagon-Like Peptide 1 (GLP-1) agonists. GLP1 agonists have been demonstrated to recruit muscle microvasculature, increase muscle delivery of insulin, and enhance the muscles use of glucose. What this means for the fitness individual is that it increases both Insulin production and sensitivity which results in stronger anabolic action of the compound and better use of glucose for muscle tissue growth. If you are looking to increase insulin sensitivity and carbohydrate utilization by muscle, a GLP-1 agonist is a peptide which has to be administered subcutaneously (under the skin). Its ability to slow down gastric emptying makes you actually want to eat less, which will be ideal for a cutting cycle or a weight and fat loss program.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113068/

Blood Flow Restriction Training

Blood Flow Restriction Training. Also known as occlusion training, is the action of simply applying an elastic band or rubber tubing around the muscle you want to target which acts like a tourniquet. Then proceed with your training. Theoretically, when you cut a small amount of blood flow to the tissue, more lactic acid accumulates faster because it doesn’t drain due to the restriction. This triggers your Growth Hormone secretion effecting more muscle building action.

A meta-analysis confirms that exercise and walking with vascular occlusion played a key role in improving strength muscle hypertrophy which is in the ball park equivalent to training high-intensity resistance training. This is compatible with those having joint pain, older fitness people and/or athletes who are recuperating from injury and just getting back into the gym.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349784/

Oxygen Restricted Training

Oxygen Restricted Training. Advance your training by biohacking your breathing. This is done by restricting your access to oxygen thereby compelling your inspiratory and expiratory muscles to work harder to take oxygen in and push carbon dioxide out.

This creates a stronger diaphragm, tougher respiratory muscles, and a higher tolerance for carbon dioxide. The “intermittent hypoxic training mask” gives you the benefits of both resisted breathing and hypoxic training—yep, like working out in an environment with reduced oxygen, like a location at high-altitude. It’s like running a marathon at Mt. Kilimanjaro. When you exercise wearing oxygen restricting mask, this can push you to a whopping 95% of lactate threshold workload. And this is a sure-fire way to improve your aerobic capacity and endurance performance once you return to normal oxygen-level environments.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243200/

YK-11 Alpha Helix. It is one of the most innovative and exciting Selective Androgen Receptor Modulators in the market right now. This unique compound stimulates Follistatin and Myogenin production- molecules that are significantly responsible for skeletal muscle development and repair.

It also inhibits Myostatin, which is a negative regulator of muscle growth and is significantly implicated in muscle-wasting disorders. What this means is that Myostatin mainly inhibits and limits muscle growth. Thanks to YK11 Alpha Helix, it blocks the action of Myostatin stopping its catabolic effects while up-regulating follistatin and myogenin activities to allow muscle tissues to grow beyond their limitations.

Like any other SARMs, YK-11 Alpha Helix can be as powerful as testosterone in terms of muscle tissue strengthening and volumisation, but without any heavy side effects as with testosterone.

https://www.elitesarms.com/collections/individual-sarms/products/alpha-helix-yk11

https://www.sciencedirect.com/science/article/pii/S0006291X21000668

Remember:

The above tools will help you achieve faster physique targets as you enhance your training protocol for superior benefits. Don’t ever think these tactics are just for professional bodybuilders and athletes, these methods are simple enough and can be adopted by anyone to working to achieve their best physique yet.

Posted on September 15, 2021September 26, 2023 by Jordan Pearce — Leave a comment

Discover The Power of Physique 400 (LGD4033)

Ligandrol, also known as LGD-4033 or Physique 400® in the Elite Sarms range, has been a favorite staple in the muscle building scene due to its reliable and consistent anabolic effects. This is due to Ligandrol’s high affinity to the androgen receptors of the bones, muscles, and connective tissues causing enhanced bone strength and accelerated muscle protein synthesis. This then equals large gains in strength and muscle mass at a highly accelerated pace compared to result times without it.

According to clinical data and anecdotal experiences, the most mentionable effects of Physique 400® are:

Lean Muscle Mass Gains
Accelerated Bulking Targets
Significant Boost in Athletic Performance
Fast increases in strength
Increased Bone Density
Enhanced Recovery Time
Improved SpeedOf Fat Loss

When tested on 76 healthy men for 21 days, LGD was safe and well tolerated, with noticeable increase in lean body mass, and despite the demonstrable androgenic activity, the serum PSA (The PSA test is a blood test used primarily to screen for prostate cancer. The test measures the amount of prostate-specific antigen (PSA) in your blood) did not change, proof that it has no adverse effects on the prostate. This only supports LGD’s low risk profile and high effectivity in low to average doses.

https://www.elitesarms.com/collections/individual-sarms/products/physique-400-lgd4033

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111291/

https://www.mayoclinic.org/tests-procedures/psa-test/about/pac-20384731#:~:text=The%20PSA%20test%20is%20a,below%20the%20bladder%20in%20males.

The Program:

The average amount of Physique 400 taken by fitness and athletic individuals is between 5 to 10 mg per day. You can take it any time throughout the day but to optimize its benefit, take 1 ml (10mg) 30 minutes before training to improve your physical strength and endurance, and accelerate recovery after. This is easily possible because Ligandrol has a half-life of 24 to 36 hrs. Which means it continues to work in your system hours and even days after taking it.

This is also the reason why you need to cycle LGD between 6-8 weeks, take a PCT for 4 weeks before starting again. LGD’s effects kick in after roughly a week. You start noticing you can push more in terms of intensity and volume during your training, you don’t feel as exhausted after a session, and you recover more quickly after an extreme workout routine. Some anecdotes report seeing a physical difference in the body as early as 2 weeks.

Physique 400® is such a potent SARM that it is not surprising to see users gain between 10 to 15 lbs (4.5kg to 6.8kg) from just one cycle when paired with the right muscle-building workout and nutritional calorie intake. For training ideas and proper nutrition tips for your muscle-building goals, read this article.

https://www.elitesarms.com/collections/individual-sarms/products/elite-sarms-re-charge-arimistane-25mg-ml-at-30ml

https://www.elitesarms.com/blogs/news/the-muscle-building-program-to-maximise-your-lean-mass-using-the-elite-sarms-builders

Busting the Myth about LGD-4033

Finally, I would like to address the ‘big fluster’ about Ligandrol causing liver toxicity. There was a reported case, and I would emphasize, one case of increased liver transaminases ‘allegedly’ caused by Ligandrol.

If you look at the study closely, even the authors admitted that:

1. No genetic testing was done to test for hepatic transporter protein abnormalities or other genetic abnormalities that can predispose the patient to drug induced liver injury.

2. They also acknowledged that it is possible that the Ligandrol the patient took had other different unapproved drugs (after all it wasn’t tests conducted with Elite Sarms – Physique 400® 😉

And according to another study, among the 44 products marketed and sold as selective androgen receptor modulators which the researchers have investigated, only 23 (52%) contained 1 or more selective androgen receptor modulators. So you really have to be careful, and smart when choosing your SARMs supplier. (BTW you can see all Elite Sarms Identification and Purity Testing within the images on each Individual Product page. These tests are conducted on each new batch of Elite Sarm individual products before they enter the manufacturing phase).

Which brings me to an important point. If you are going to buy Ligandrol online, it is very important to verify the purity of the product you are going to purchase. Ligandrol is safe to use with the daily dose we recommended—as long as it’s the real deal!!!

One way to know the quality of your SARMs product is to check for the COA (Certificate Of Analysis) done by an independent or 3rd party laboratory, meaning the testing is not conducted by the company selling the product, so no false results can be reproduced and marketed to you. If it’s not posted on the website, don’t be afraid to ask for the Certificate of Analysis. SARMs are research compounds, and it is absolutely your right to verify their purity before you part with your hard earned money.

At Elite Sarms we are proud to display the quality of our ingredients before they even reach our highly qualified medical scientists for manufacturing, as the industry is littered with false products, fakes and scammers and we are here to clean things up, make things right and serve you, the people exactly what you are paying for and not a mg or purity percentage under that.

Train hard, ES.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304490/

https://pubmed.ncbi.nlm.nih.gov/29183075/

https://www.elitesarms.com/collections/individual-sarms/products/physique-400-lgd4033

Posted on September 8, 2021May 30, 2024 by Jordan Pearce — Leave a comment

Muscle Building Marvel – RAD140

Written by: Michelle G. Thibault
Edited by: Ryan McTeigue

RAD140, popularly known as Elite Sarms TIGHT®, is an investigational compound, which has become popular among bodybuilders, sports people and fitness enthusiasts. When looking to buy SARMs for fat loss and muscle gain, TIGHT® RAD 140 is an easy choice. It is reputed to have muscle-building and strength enhancing effects due to its high affinity with androgen receptors found in skeletal muscles, bones and connective tissues.

For those who are not so familiar with RAD 140, this article highlights the history and discovery of RAD140, and the mechanism behind why it is now considered to be Testosterone’s equal in terms of its anabolic properties – no jokes, this is what the new science is revealing to us.

RAD 140 is a potent, orally bioavailable Androgen Receptor Modulator (SARM) compound that was developed by Radius Health, Inc. It was originally designed as an experimental substance for androgen replacement therapy. Some of the potential benefits of RAD140 being tested within the research studies just to name a few; were for the treatment of conditions such as muscle wasting (cachexia), bone loss, and breast cancer. You can start to build a picture of how this product has come to be one of the most potent muscle building compounds while being non-steroidal.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018048/

https://www.elitesarms.com/collections/individual-sarms/products/tight-rad-140

RAD 140’s Special Features

Tissue selectivity. The tissue selectivity of RAD140 is shown by potent androgen-like properties in bone and muscle, which is mainly anabolic. Studies demonstrated an increase in the weight of the pelvic muscles of castrated rats compared to control groups with RAD140‘s lowest tested dose of 0.1 mg/kg. Impressive!

The physique and sports scene caught on very rapidly to the muscle building effects of RAD 140 making it a popular choice when buying SARMs in USA, Canada and the EU.

However, it demonstrates diminished effects in other androgen-responsive tissues, such as prostate and seminal vesicles – this is a great thing and the reason why it doesn’t cause prostate hypertrophy or infertility.

Particularly, when administered along with testosterone, RAD140 was found to somewhat antagonize the growth effect of testosterone in prostate and seminal vesicles, proposing that RAD140 acts as a competitive Androgen Receptor ligand but with reduced activity. This means that RAD140 successfully competes with Testostorone on AR sites blocking the hormone from attaching to these negative receptor sites, thus inhibiting synthetic testosterones potential tumor-promoting actions on reproductive organs. Tight® therefore, may be effective in use as protection of the prostate and other sensitive reproductive organ sites that high and long doses or testosterone have the potential to negatively effect. Ie RAD140 could be used along-side testosterone to not only enhance the positive effects but to also block any potential negative effects the synthetic testosterone can cause.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083371/

Safety. The same study also found that while taking RAD140, despite the dramatic increases in body weight over such a short time, there was no elevation of liver enzyme transaminase levels in any of the lab mice at any dose >2 fold over its baseline value. Given the established link between oral androgen use and liver stress indicators, researchers were pleasantly surprised that even at a dose 10x greater than the fully effective dose, they saw minimal liver enzyme elevations with RAD140 – this is another very positive finding.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018048/

https://www.elitesarms.com/collections/individual-sarms/products/tight-rad-140

It is Neuroprotective too!

When testosterone levels in men start to fall due to the normal aging process, the risks of dysfunction and disease in androgen-responsive tissues increases, which amazingly, also includes the brain!! After all the brain is a large organ made up of proteins such like any other organ in the body except is carries out a much grander role – allowing us to experience reality.

Since testosterone therapy can cause a potential increase in the risk of developing prostate cancer, scientists have turned to SARMs to overcome these limitations. Studies have discovered that RAD140 lacks significant androgen action in the prostate (the main hardware in the reproductive system) but exerts highly positive effects in selective androgen-responsive tissues including BRAIN NEURONS!

In a 2014 study by the Endocrine Society, RAD140’s effects were investigated in cultured rat neurons and male rat brain. RAD140 was shown to provide neuroprotection, and increased resilience from neurodegenerative diseases.

The study concluded, that by administering RAD140, it activates androgen-protective pathways that reduce cell death induced by 3 factors: Aβ peptides (coming from amyloid deposits seen in Alzheimer’s), apoptosis activator II (seen in tumor and cancer cells), and hydrogen peroxide (produced during cell injury).

Like Testosterone, RAD140 has the ability to protect the brain but also help it to function / perform better. However unlike Testosterone, RAD140 is extremely highly selective, activating androgen receptors in the muscles we use to work out and the brain tissue we use to develop business ideas, and in-general just think and continue being able to think effectively, long into our years.

We here are Elite Sarms believe we are only just looking at the tip of the ice-burg with the muscle building Marvel – RAD140 and we are exciting to continue bringing you research on what the studies continue to reveal about this amazing compound. In the meantime if you would like to conduct your own personal research and see what this amazing compound can do for your physique and for your brain performance, check out Elite Sarms Tight® (RAD140) here.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959610/

https://pubmed.ncbi.nlm.nih.gov/16011741/